Protein Alignment Cyp4e1 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 522
• Identity: 130/522 - (24%)
• Similarity: 246/522 - (47%)
• Gaps: 81/522 - (15%)

  Fly     2 WIVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWW--- 63
            |::|...|.| |:.......||.:::.:    .||..||.:|.          :||.:.|.|
Mouse    12 WVLLAIILVL-LYRYGTRTHGLFKKQGI----PGPKPLPFLGT----------VLNYYKGLWKFD 61

  Fly    64 ----HEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLT-----S 119
                .:||| .:..:.|.....::|:|:.::.:|..:..    .|:.....:..:|:::     |
Mouse    62 MECYEKYGK-TWGLFDGQMPLFVITDPEMIKNVLVKECF----SVFTNRREFGPVGIMSKAISIS 121

  Fly   120 TGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICD 184
            ...:|.::|.:::|.|....|::...|:.:.....:..|.:.|:.|.....::.....::|||..
Mouse   122 KDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITS 186

  Fly   185 TAMGVSINAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHF-APEY--------PEYSKTL 240
            |:.||:::::.|.....|:..|.|   :::..|.|...:..||.| .|.|        |:.|  :
Mouse   187 TSFGVNVDSLNNPEDPFVEKAKGI---LRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDS--I 246

  Fly   241 KTLQDFTNEIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSS------KVDGRPLTSQELYE 299
            :..:.|.|.:...|:             |...:.::.||..::::      |...:.|:..|:..
Mouse   247 EFFKKFVNRMKESRL-------------DSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITA 298

  Fly   300 EVSTFMFEGHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLF 364
            :...|:|.|::||:|.:.|.:|.|:.|||.|:||..|..:.:....   ..|:..:..|::||:.
Mouse   299 QSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKA---PPTYDTVMEMEYLDMV 360

  Fly   365 IKEAQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP 429
            :.|..||||....:.||.:||..::|..:|||:|:.:....|.::.:.:.:|.:||||||.:|..
Mouse   361 LNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENK 425

  Fly   430 G---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV----SKDGYISTTLGL 487
            |   |:.|:||..|||||||.:||.:.:|..::|:::||...|..:..:    |:.|.      |
Mouse   426 GSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGL------L 484

  Fly   488 QP 489
            ||
Mouse   485 QP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	112/449 (25%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	114/452 (25%)