Protein Alignment Cyp4e1 and cyp24a1

DIOPT Version :10

• Sequence 1: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001082927.1
• Gene: cyp24a1 / 100004700
• ZFINID: ZDB-GENE-060825-1
• Length: 505
• Species: Danio rerio
• Alignment Length: 499
• Identity: 133/499 - (26%)
• Similarity: 211/499 - (42%)
• Gaps: 98/499 - (19%)

  Fly    30 LNKFQGPSMLPLVGNAHQMGNTPTEILNRFFGWWHE--------YGKDNFRYWIGYYSNIMVTNP 86
            |:...||:..||.|:..::      |.|......||        :|| .||..:|.:.::.:.:|
Zfish    49 LDSIPGPTNWPLFGSLIEV------IRNGGLKRQHETLIHFHKKFGK-IFRMKLGSFESVHIGSP 106

  Fly    87 KYMEFILSSQTLISKSDVYD---LTHPWL--------GLGLLTSTGSKWHKHRKMITPAFHFNIL 140
            ..:|      .|..|...|.   ...||.        ..|||...|..|.:.|.    ||...::
Zfish   107 CLLE------ALYRKEGSYPERLEIKPWKAYRDMRDEAYGLLILEGRDWQRVRS----AFQQKLM 161

  Fly   141 QDFHEVM------NENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVIC----DTAMGVSINAME 195
            :. .|||      ||.:...|.::.||  .|.:.....|.:..:.:.||    |...|:..:::.
Zfish   162 KP-TEVMKLDGKINEVAADLIKRIGKV--NGKMDALYFELNKWSFETICYVIYDKRFGLLQDSVS 223

  Fly   196 NRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTL--KTLQDFT----------N 248
            ......:.|.|.:..|......:|              .|..|||  ||.:|.|          .
Zfish   224 KEGMDFITAVKTMMSTFGTMMVTP--------------VELHKTLNTKTWKDHTEAWDRIFSTAK 274

  Fly   249 EIIAKRIEVRKSGLEVGIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTT 313
            ..|.|.::.:.:|     :||:|           ||.......||.:|||...:.....|.:||.
Zfish   275 HYIDKNLQKQSNG-----EADDF-----------LSDIFHNGNLTKKELYAATTELQVGGVETTA 323

  Fly   314 SGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFI 378
            :.:.:.::.|||:|..|.||..|..||:.|   |:....:.|.:|.:|...:||:.|:.|||||.
Zfish   324 NSMLWVIFNLSRNPCAQGKLLKEIQDVVPA---GQTPRAEHIKSMPYLKACLKESMRVSPSVPFT 385

  Fly   379 GRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP--GPFEYVPFSAGP 441
            .|..:||.|:....:||||.|.|....:|.::..|.:..:|:|||:..||.  .||.:|||..|.
Zfish   386 SRTLDKDTVLGDYTLPKGTVLMLNSQAIGVSEEYFDNGRQFRPERWLEEKSSINPFAHVPFGVGK 450

  Fly   442 RNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTL 485
            |.|||::.|.|:|:..:..|:|:::::..  :|...|...|.||
Zfish   451 RMCIGRRLAELQIQLGLCWILRDYKIVAT--DLEPVDSLHSGTL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	122/453 (27%)
cyp24a1	NP_001082927.1	CYP24A1	84..499	CDD:410738	123/458 (27%)