Protein Alignment Ag5r and CRISP1

DIOPT Version :10

• Sequence 1: NP_524770.1
• Gene: Ag5r / 44631
• FlyBaseID: FBgn0015010
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001122.2
• Gene: CRISP1 / 167
• HGNCID: 304
• Length: 249
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 53/228 - (23%)
• Similarity: 81/228 - (35%)
• Gaps: 50/228 - (21%)

  Fly    49 ATLLTLSSAEK-------DALVARTNEYRNHIAGGLNA----NLSAACRMATIKWNDELAYLASL 102
            |.||.:.|.:|       :.||......:..|....||    .:..|..|..:.|::|.|..|.:
Human    13 ACLLPMLSMKKKSARDQFNKLVTDLPNVQEEIVNIHNALRRRVVPPASNMLKMSWSEEAAQNARI 77

  Fly   103 NVKSCQMKHDG-----CHNTDAFDWSGQNLAWMGYYNPLNVTHY-LEWG--VDMWYDEAVYTKQA 159
            ..|.|.|....     ..||    :.|:|         :::|.| :.|.  :.:||.|:...|..
Human    78 FSKYCDMTESNPLERRLPNT----FCGEN---------MHMTSYPVSWSSVIGVWYSESTSFKHG 129

  Fly   160 YIDAYPSNYNGPAIGHFTVLVADRNTEVGCAAATYSVSGQSYKAFLLACNYA------ATNVLGI 218
               .:.:..:.....|:|.:|...:..:|||.|  |...|....:|..|:|.      .|.....
Human   130 ---EWTTTDDDITTDHYTQIVWATSYLIGCAIA--SCRQQGSPRYLYVCHYCHEGNDPETKNEPY 189

  Fly   219 KMYSSCSKAASKCTTG--TNPKYKYLCSAKEEY 249
            |....|....|.|...  |||     |...:||
Human   190 KTGVPCEACPSNCEDKLCTNP-----CIYYDEY 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ag5r	NP_524770.1	CAP_euk	59..211	CDD:349399	37/170 (22%)
CRISP1	NP_001122.2	Complex1_LYR_SF	<16..56	CDD:477356	8/39 (21%)
		CAP_CRISP	39..177	CDD:349402	35/155 (23%)
		Crisp	195..249	CDD:462519	9/28 (32%)