Protein Alignment CG14630 and TMLHE

DIOPT Version :9

• Sequence 1: NP_651985.1
• Gene: CG14630 / 44620
• FlyBaseID: FBgn0014903
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_060666.1
• Gene: TMLHE / 55217
• HGNCID: 18308
• Length: 421
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 107/385 - (27%)
• Similarity: 175/385 - (45%)
• Gaps: 38/385 - (9%)

  Fly    28 DYVEVQEEQGNLLKYPQVWLRDNCQCAECFHAATRARKSHWDRGPLNIPVSQVAYNKERKQLEII 92
            |:.|: :....::::..|||||:|:.|.|:::.|..|.  .|...:::.:.......:...|...
Human    58 DHFEL-KYANTVMRFDYVWLRDHCRSASCYNSKTHQRS--LDTASVDLCIKPKTIRLDETTLFFT 119

  Fly    93 WQDKHRSTFDLGWLRERDFGETGRKHYLEEVYKPPAQLWGKTEFEDVK-REFQYEDVLEQDAALR 156
            |.|.|.:.:||.||.:..:  .|:|   ::|.:|.. ||....::..: .....:..||.:..|:
Human   120 WPDGHVTKYDLNWLVKNSY--EGQK---QKVIQPRI-LWNAEIYQQAQVPSVDCQSFLETNEGLK 178

  Fly   157 VWLEALAVQGFAILKGAPNDINVAKKLAERIGYIKRTTYGDVFEVKSKPNARNYAYLMTPLPLHT 221
            .:|:...:.|.|.::..|......:||||||..|:.|.||.::...|..:..:.||....|..||
Human   179 KFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHT 243

  Fly   222 DMPYYEYKAGINILHTLVQSESKGGANTLTDGFNVASQLQKLHPEDFEVLKSVPVNW---FDIG- 282
            |..|::...||.:.|.| :.|..||...|.|||..|.|:.:..||:||:|..||:..   .|:|
Human   244 DTTYFQEPCGIQVFHCL-KHEGTGGRTLLVDGFYAAEQVLQKAPEEFELLSKVPLKHEYIEDVGE 307

  Fly   283 -HDGDDSKPFHSLWRAPVICL-DVDGRFARINQNTTKRDSRFSVSLAQAVSWYKAYDKF-LEIAQ 344
             |:       |.:...||:.: ..:.....|..|...|....:|.......||.|:... :|:.:
Human   308 CHN-------HMIGIGPVLNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTIELRR 365

  Fly   345 SEAVEF--KTQAGDVFVFNNLRMLHGR---TAYEDAPGNKRHLVGAYVDWDIIYSKLRTL 399
            .|. ||  |.:.|.|...:|.|:||||   |.|       |.|.|.|:..|.:.:..|.|
Human   366 PEN-EFWVKLKPGRVLFIDNWRVLHGRECFTGY-------RQLCGCYLTRDDVLNTARLL 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14630	NP_651985.1	carnitine_bodg	30..400	CDD:274118	106/383 (28%)
		DUF971	<41..107	CDD:294847	18/65 (28%)
		CAS_like	120..390	CDD:238154	81/282 (29%)
TMLHE	NP_060666.1	carnitine_TMLD	70..419	CDD:274119	105/372 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2175
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D534559at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2023
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850