| Sequence 1: | NP_001188547.1 | Gene: | MAPk-Ak2 / 44573 | FlyBaseID: | FBgn0013987 | Length: | 359 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_116584.2 | Gene: | MAPKAPK2 / 9261 | HGNCID: | 6887 | Length: | 400 | Species: | Homo sapiens |
| Alignment Length: | 342 | Identity: | 217/342 - (63%) |
|---|---|---|---|
| Similarity: | 276/342 - (80%) | Gaps: | 0/342 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 9 QPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVSGCRYI 73
Fly 74 VNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDI 138
Fly 139 AHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIW 203
Fly 204 SLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSK 268
Fly 269 RLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEMTRSLATMRVDYDQMQIKALDK 333
Fly 334 SNNPLLTKRRKKIEEME 350 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MAPk-Ak2 | NP_001188547.1 | STKc_MAPKAPK | 18..280 | CDD:270991 | 172/261 (66%) |
| S_TKc | 25..281 | CDD:214567 | 170/255 (67%) | ||
| MAPKAPK2 | NP_116584.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..43 | ||
| STKc_MAPKAPK2 | 61..363 | CDD:271072 | 196/301 (65%) | ||
| Staurosporine binding | 139..141 | 1/1 (100%) | |||
| Autoinhibitory helix. /evidence=ECO:0000250 | 328..364 | 21/35 (60%) | |||
| Nuclear export signal (NES) | 356..365 | 6/8 (75%) | |||
| p38 MAPK-binding site | 366..390 | 13/23 (57%) | |||
| Bipartite nuclear localization signal 1 | 371..374 | 1/2 (50%) | |||
| Bipartite nuclear localization signal 2 | 385..389 | 3/3 (100%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 377 | 1.000 | Domainoid score | I863 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0604 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 467 | 1.000 | Inparanoid score | I1545 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG52456 | |
| OrthoDB | 1 | 1.010 | - | - | D363028at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002999 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42269 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105148 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24349 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4637 |
| SonicParanoid | 1 | 1.000 | - | - | X1992 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.870 | |||||