DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CPK29

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_974150.2	Gene:	CPK29 / 843936	AraportID:	AT1G76040	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	354	Identity:	109/354 - (30%)
Similarity:	162/354 - (45%)	Gaps:	46/354 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LGYGINGKVVQCTHRRTQQNYALKVL--------LDSERARREVDLHWRVSGCRYIVNIIDVYEN 82
            ||.|..|...:||.:...:.||.|.:        .|.|..||||.:...::|...||.....||
plant   118 LGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEFRGAYE- 181

  Fly    83 TFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPEN 147
               |:..|.:|||...|||||.||..|  |:::|:|||.|..:|...|...|...:.||||||||
plant   182 ---DKDNLHLVMELCSGGELFDRIIKK--GSYSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPEN 241

  Fly   148 LLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVVMYII 212
            .|..:.:.::.:|.||||.:.........:....:.|||||||| ...|.|..|:||.||::||:
plant   242 FLLVSNEEDSPIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVL-HRNYGKEIDVWSAGVMLYIL 305

  Fly   213 MCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVIS 277
            :.|.|||:......|.    ..|..|:.|.....|..:|::|||||:.||..||.||:...:.:.
plant   306 LSGVPPFWGETEKTIF----EAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALE 366

  Fly   278 NKWIA------------------QYNAVPQTPLCTGRMLKEAEETWPEVQEEMTRSL--ATMRVD 322
            :.|:.                  |:.|:.:......:::.|      .:.||..:.|  ....:|
plant   367 HPWMTDTKISDKPINSAVLVRMKQFRAMNKLKKLALKVIAE------NLSEEEIKGLKQTFKNMD 425

  Fly   323 YDQMQIKALDKSNNPLLTKRRKKIEEMEL 351
            .|:......|:..|. |.:...|:.|.|:
plant   426 TDESGTITFDELRNG-LHRLGSKLTESEI 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	94/261 (36%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	94/262 (36%)
CPK29	NP_974150.2	S_TKc	112..370	CDD:214567	94/262 (36%)
		STKc_CAMK	112..369	CDD:270687	94/261 (36%)
		PTZ00184	405..548	CDD:185504	12/56 (21%)
		EFh	417..476	CDD:238008	9/38 (24%)
		EFh	489..549	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100