DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MAPk-Ak2 and CPK19

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_176386.2	Gene:	CPK19 / 842490	AraportID:	AT1G61950	Length:	551	Species:	Arabidopsis thaliana

Alignment Length:	355	Identity:	117/355 - (32%)
Similarity:	175/355 - (49%)	Gaps:	44/355 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LGYGINGKVVQCTHRRTQQNYALKVLL--------DSERARREVDLHWRVSGCRYIVNIIDVYEN 82
            ||.|..|....||...:.:|:|.|.:|        |.|..|||:.:...:||...||.|...||
plant   104 LGRGQFGITYICTEISSGKNFACKSILKRKLIRTKDREDVRREIQIMHYLSGQPNIVEIKGAYE- 167

  Fly    83 TFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPEN 147
               ||:.:.:|||..||||||.:|..:  |.::|:.||:|:..:...|...|...:.||||||||
plant   168 ---DRQSVHLVMELCEGGELFDKITKR--GHYSEKAAAEIIRSVVKVVQICHFMGVIHRDLKPEN 227

  Fly   148 -LLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVLGPEKYDKSCDIWSLGVVMYI 211
             ||.:..:.::.||.||||.:.........:....:.|||||||| ...|.|:.||||.||::||
plant   228 FLLSSKDEASSMLKATDFGVSVFIEEGKVYEDIVGSAYYVAPEVL-KRNYGKAIDIWSAGVILYI 291

  Fly   212 IMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVI 276
            ::||.|||::.    ...|:...|..|:.||....|.::|::||||::.||..||.||.....|:
plant   292 LLCGNPPFWAE----TDKGIFEEILRGEIDFESEPWPSISESAKDLVRNMLKYDPKKRFTAAQVL 352

  Fly   277 SNKWIAQYNAVPQTPL---CTGRM--------LKEAEETW--PEVQEEMTRSLATM--------- 319
            .:.||.:.......|:   ...||        ||:....:  ..::||..:.|.||
plant   353 EHPWIREGGEASDKPIDSAVLSRMKQLRAMNKLKKLAFKFIAQNLKEEELKGLKTMFANMDTDKS 417

  Fly   320 -RVDYDQMQIKALDKSNNPLLTKRRKKIEE 348
             .:.||::: ..|:|..:.|.....|::.|
plant   418 GTITYDELK-SGLEKLGSRLTETEVKQLLE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	98/262 (37%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	98/263 (37%)
CPK19	NP_176386.2	STKc_CAMK	97..356	CDD:270687	98/262 (37%)
		Pkinase	98..357	CDD:278497	98/263 (37%)
		PTZ00184	393..538	CDD:185504	12/55 (22%)
		EFh	405..464	CDD:238008	10/43 (23%)
		EFh	477..537	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100