DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CDPK2

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_174807.1	Gene:	CDPK2 / 840471	AraportID:	AT1G35670	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	368	Identity:	120/368 - (32%)
Similarity:	177/368 - (48%)	Gaps:	43/368 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NQRQPKT------TPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVL--------LDSER 56
            |.|:|..      ||...|:......||.|..|....||.:.|..|||.|.:        .|.|.
plant     6 NPRRPSNTVLPYQTPRLRDHYLLGKKLGQGQFGTTYLCTEKSTSANYACKSIPKRKLVCREDYED 70

  Fly    57 ARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQ 121
            ..||:.:...:|....:|.|    :.|::|...:.:|||..||||||.||..|  |.|:||||.:
plant    71 VWREIQIMHHLSEHPNVVRI----KGTYEDSVFVHIVMEVCEGGELFDRIVSK--GHFSEREAVK 129

  Fly   122 IMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYV 186
            ::..|...|:..||..:.||||||||.|:.:.:.:|.||.||||.:........|.....:||||
plant   130 LIKTILGVVEACHSLGVMHRDLKPENFLFDSPKDDAKLKATDFGLSVFYKPGQYLYDVVGSPYYV 194

  Fly   187 APEVL----GPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEW 247
            |||||    |||     .|:||.||::||::.|.|||::.    ...|:..:|..|:.||....|
plant   195 APEVLKKCYGPE-----IDVWSAGVILYILLSGVPPFWAE----TESGIFRQILQGKLDFKSDPW 250

  Fly   248 TNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEM 312
            ..:|:||||||..||...|.||:...:.:.:.||....|.|..||....:.:..:.:.....::|
plant   251 PTISEAAKDLIYKMLERSPKKRISAHEALCHPWIVDEQAAPDKPLDPAVLSRLKQFSQMNKIKKM 315

  Fly   313 TRSLATMRVDYDQM-----QIKALDKSNNPLLTKRRKKIEEME 350
            ...:...|:..:::     ..|.:|..|:..:|     .||::
plant   316 ALRVIAERLSEEEIGGLKELFKMIDTDNSGTIT-----FEELK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	101/273 (37%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	100/267 (37%)
CDPK2	NP_174807.1	STKc_CAMK	25..283	CDD:270687	100/272 (37%)
		Pkinase	26..284	CDD:278497	100/272 (37%)
		PTZ00184	320..462	CDD:185504	7/39 (18%)
		EFh	332..391	CDD:238008	6/27 (22%)
		EFh	404..463	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010