DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CDPK9

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_197748.1	Gene:	CDPK9 / 832424	AraportID:	AT5G23580	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	299	Identity:	113/299 - (37%)
Similarity:	164/299 - (54%)	Gaps:	38/299 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVL--------LDSERARREVDLHWRV 67
            ||..:.|:|.... |||.|..|....|||::|.|..|.|.:        .|.:...||:.:...:
plant    14 KTKNVEDNYFLGQ-VLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLREIQIMHHL 77

  Fly    68 SGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDY 132
            |....:|.|    |:.::|.|.:.:|||..||||||.||..:  |.::|||||:::..|...|:.
plant    78 SEYPNVVRI----ESAYEDTKNVHLVMELCEGGELFDRIVKR--GHYSEREAAKLIKTIVGVVEA 136

  Fly   133 LHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFA-----KETFTSYTLQTPCYTPYYVAPEVL- 191
            .||..:.||||||||.|::::..:|:||.||||.:     .|.|:...     .:.||||||||
plant   137 CHSLGVVHRDLKPENFLFSSSDEDASLKSTDFGLSVFCTPGEAFSELV-----GSAYYVAPEVLH 196

  Fly   192 ---GPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQA 253
               |||     ||:||.||::||::||||||::...:    |:..:|..|:.:|....|.::|::
plant   197 KHYGPE-----CDVWSAGVILYILLCGFPPFWAESEI----GIFRKILQGKLEFEINPWPSISES 252

  Fly   254 AKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPL 292
            ||||||.||..:|.|||....|:.:.||......|..||
plant   253 AKDLIKKMLESNPKKRLTAHQVLCHPWIVDDKVAPDKPL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	105/278 (38%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	104/272 (38%)
CDPK9	NP_197748.1	STKc_CAMK	21..279	CDD:270687	105/278 (38%)
		Pkinase	22..280	CDD:278497	105/278 (38%)
		PTZ00184	316..458	CDD:185504
		EFh	328..387	CDD:238008
		EFh	400..459	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010