DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CPK18

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001190932.1	Gene:	CPK18 / 829763	AraportID:	AT4G36070	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	357	Identity:	103/357 - (28%)
Similarity:	172/357 - (48%)	Gaps:	39/357 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVL--------LDSERARREVDLHWRVSGCRYI 73
            |:..|...:||:|..|.....|........|:|.:        ::.|..:|||.:...:.|...:
plant    68 DNRYTIGKLLGHGQFGFTYVATDNNNGNRVAVKRIDKAKMTQPIEVEDVKREVKILQALGGHENV 132

  Fly    74 VNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDI 138
            |.    :.|.|:|:..:.:|||..:||||..||..|.|..:||::||.::.::.......|.|.:
plant   133 VG----FHNAFEDKTYIYIVMELCDGGELLDRILAKKDSRYTEKDAAVVVRQMLKVAAECHLRGL 193

  Fly   139 AHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVL----GPEKYDKS 199
            .|||:||||.|:.:|:..::||.||||.:.........|....:.||||||||    |||.
plant   194 VHRDMKPENFLFKSTEEGSSLKATDFGLSDFIKPGVKFQDIVGSAYYVAPEVLKRRSGPES---- 254

  Fly   200 CDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNV 264
             |:||:||:.||::||..||:..    ...|:.|.:...:.||.:..|..:|..|||.:|.:|..
plant   255 -DVWSIGVITYILLCGRRPFWDK----TQDGIFNEVMRKKPDFREVPWPTISNGAKDFVKKLLVK 314

  Fly   265 DPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEE--TWPEVQEEMTRSLATMRVDYDQM- 326
            :|..||.....:|:.|:.:.....:.|:... :|....:  .:..:::...|:|| ..::.|::
plant   315 EPRARLTAAQALSHSWVKEGGEASEVPIDIS-VLNNMRQFVKFSRLKQIALRALA-KTINEDELD 377

  Fly   327 ----QIKALDKSNNPLLTKRRKKIEEMELYMA 354
                |..|:|...|..::     :|||...:|
plant   378 DLRDQFDAIDIDKNGSIS-----LEEMRQALA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	87/273 (32%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	86/267 (32%)
CPK18	NP_001190932.1	STKc_CAMK	70..330	CDD:270687	87/272 (32%)
		S_TKc	71..331	CDD:214567	87/272 (32%)
		PTZ00184	367..514	CDD:185504	11/44 (25%)
		EFh	378..437	CDD:238008	8/32 (25%)
		EFh	459..513	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100