DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CPK27

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_192379.2	Gene:	CPK27 / 825805	AraportID:	AT4G04700	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	361	Identity:	105/361 - (29%)
Similarity:	173/361 - (47%)	Gaps:	49/361 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QNQRQPKTTPLTDDYVTSNTVLG-------YGINGKVVQCTHRRTQQNYALKVLLDS-------- 54
            |::|.....||.|  :|...:||       :|:..|   |..:.|.:.:|.|.:|.:
plant    11 QSKRTILEKPLVD--ITKIYILGEELGRGNFGLTRK---CVEKSTGKTFACKTILKTKLKDEECE 70

  Fly    55 ERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKAD--GAFTER 117
            |..:||:.:..::||   ..||:: ::|.::|:..:.:|||...||||:.:|....|  .:::|:
plant    71 EDVKREIRIMKQLSG---EPNIVE-FKNAYEDKDSVHIVMEYCGGGELYDKILALYDVGKSYSEK 131

  Fly   118 EAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYT 182
            |||.|:..|...|...|...:.||||||||.|.|:...|||:|:.|||.:.........|....:
plant   132 EAAGIIRSIVNVVKNCHYMGVMHRDLKPENFLLTSNDDNATVKVIDFGCSVFIEEGKVYQDLAGS 196

  Fly   183 PYYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEW 247
            .||:||||| ...|.|..||||.|:::||::||..||....    ...|.|.|::.:.|:.:..|
plant   197 DYYIAPEVL-QGNYGKEADIWSAGIILYILLCGKSPFVKEP----EGQMFNEIKSLEIDYSEEPW 256

  Fly   248 TNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNA----VPQTPLCTGRMLKEAEE----- 303
            ......|..|:|.||:.:|.:|:...:|:.:.|:.:..|    :....|...:..::|.:
plant   257 PLRDSRAIHLVKRMLDRNPKERISAAEVLGHPWMKEGEASDKPIDGVVLSRLKRFRDANKFKKVV 321

  Fly   304 ---TWPEVQEEMTRSLATMRVDYDQMQIKALDKSNN 336
               ....:.||..:.|.|:..:.|      .|||.|
plant   322 LKFIAANLSEEEIKGLKTLFTNID------TDKSGN 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	87/278 (31%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	86/272 (32%)
CPK27	NP_192379.2	S_TKc	28..290	CDD:214567	86/273 (32%)
		STKc_CAMK	28..289	CDD:270687	86/272 (32%)
		PTZ00184	325..468	CDD:185504	9/33 (27%)
		EFh	337..396	CDD:238008	7/21 (33%)
		EFh	411..469	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100