DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CRK

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001190048.1	Gene:	CRK / 824217	AraportID:	AT3G50530	Length:	632	Species:	Arabidopsis thaliana

Alignment Length:	353	Identity:	110/353 - (31%)
Similarity:	160/353 - (45%)	Gaps:	57/353 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 QNYALKVL--------LDSERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGG 100
            |..|:||:        :..|..||||.:...:||...:.:..|.||    |...:.:|||..|||
plant   175 QQVAVKVIPKAKMTTAIAIEDVRREVKILRALSGHNNLPHFYDAYE----DHDNVYIVMELCEGG 235

  Fly   101 ELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFG 165
            ||..||..:. |.:||.:|..:|.:|...|.:.|.:.:.||||||||.|:|:.:..:.||..|||
plant   236 ELLDRILSRG-GKYTEEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLFTSKEDTSQLKAIDFG 299

  Fly   166 FAK---------------------ET----------FTSYTLQTPCYTPYYVAPEVLGPEKYDKS 199
            .:.                     ||          |....|.....:.|||||||| ...|...
plant   300 LSDYVRPGKALRLYAICKLRFQNLETSICLYALTIAFADERLNDIVGSAYYVAPEVL-HRSYSTE 363

  Fly   200 CDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGMLNV 264
            .||||:||::||::||..||::.    ...|:...:......|.||.|..:|..|:|.:|.:||.
plant   364 ADIWSVGVIVYILLCGSRPFWAR----TESGIFRAVLKADPSFDDPPWPLLSSEARDFVKRLLNK 424

  Fly   265 DPSKRLRIQDVISNKWIAQYN--AVPQTPLCTGRMLKEAEETWPEVQEEMTRSLA-TMRVD---Y 323
            ||.|||.....:|:.||...|  .||...|..  .|..|......:::...|:|: |:.||   |
plant   425 DPRKRLTAAQALSHPWIKDSNDAKVPMDILVF--KLMRAYLRSSSLRKAALRALSKTLTVDELFY 487

  Fly   324 DQMQIKALDKSNNPLLTKRRKKIEEMEL 351
            .:.|...|:.|.|..::....|...|::
plant   488 LREQFALLEPSKNGTISLENIKSALMKM 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	90/274 (33%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	90/275 (33%)
CRK	NP_001190048.1	STKc_CAMK	147..440	CDD:270687	90/274 (33%)
		S_TKc	148..441	CDD:214567	90/275 (33%)
		Glo_EDI_BRP_like	526..>597	CDD:301325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100