DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAPk-Ak2 and CPK2

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001326044.1	Gene:	CPK2 / 820235	AraportID:	AT3G10660	Length:	646	Species:	Arabidopsis thaliana

Alignment Length:	367	Identity:	111/367 - (30%)
Similarity:	178/367 - (48%)	Gaps:	40/367 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LSLQNQRQPKTTPLTDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALKVLL--------DSERAR 58
            |..::..|.||....:.| :....||.|..|....|..:.|...||.|.:.        |.|..|
plant   169 LRTESVLQRKTENFKEFY-SLGRKLGQGQFGTTFLCLEKGTGNEYACKSISKRKLLTDEDVEDVR 232

  Fly    59 REVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIM 123
            ||:.:...::|...:::|...||    |...:.:|||...|||||.||..:  |.:|||:||::.
plant   233 REIQIMHHLAGHPNVISIKGAYE----DVVAVHLVMELCSGGELFDRIIQR--GHYTERKAAELA 291

  Fly   124 HEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFA-----KETFTSYTLQTPCYTP 183
            ..|...::..||..:.||||||||.|:.:.:.::.||..|||.:     .|.||...     .:|
plant   292 RTIVGVLEACHSLGVMHRDLKPENFLFVSREEDSLLKTIDFGLSMFFKPDEVFTDVV-----GSP 351

  Fly   184 YYVAPEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWT 248
            |||||||| .::|....|:||.||::||::.|.|||::.    ...|:..::..|..||....|.
plant   352 YYVAPEVL-RKRYGPESDVWSAGVIVYILLSGVPPFWAE----TEQGIFEQVLHGDLDFSSDPWP 411

  Fly   249 NVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAEETWPEVQEEM- 312
            ::|::||||::.||..||.:||....|:.:.|:......|..||.:..:.:..:.:.....::|
plant   412 SISESAKDLVRKMLVRDPKRRLTAHQVLCHPWVQIDGVAPDKPLDSAVLSRMKQFSAMNKFKKMA 476

  Fly   313 ----TRSLATMRVDYDQMQIKALDKSNNPLLTKRRKKIEEME 350
                ..||:...:...:...|.:|..|:..:|     .||::
plant   477 LRVIAESLSEEEIAGLKQMFKMIDADNSGQIT-----FEELK 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	94/274 (34%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	93/268 (35%)
CPK2	NP_001326044.1	PspC_subgroup_2	<45..>159	CDD:411408
		STKc_CAMK	185..443	CDD:270687	94/274 (34%)
		PTZ00184	480..622	CDD:185504	8/39 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010