DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MAPk-Ak2 and CPK16

DIOPT Version :9

Sequence 1:	NP_001188547.1	Gene:	MAPk-Ak2 / 44573	FlyBaseID:	FBgn0013987	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_179379.1	Gene:	CPK16 / 816299	AraportID:	AT2G17890	Length:	571	Species:	Arabidopsis thaliana

Alignment Length:	384	Identity:	109/384 - (28%)
Similarity:	183/384 - (47%)	Gaps:	50/384 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSLQNQRQPKTTPL-----------TDDYVTSNTVLGYGINGKVVQCTHRRTQQNYALK----- 49
            ::|...:|..:|.|.           .|...|...:||:|..|.....|.::|....|:|
plant    78 VISNNGRRHGETIPYGKRVDFGYAKDFDHRYTIGKLLGHGQFGYTYVATDKKTGDRVAVKKIDKA 142

  Fly    50 ---VLLDSERARREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKAD 111
               :.:..|..:|||.:...::|..   |::..| |.|:|:..:.:|||..|||||..||..:.|
plant   143 KMTIPIAVEDVKREVKILQALTGHE---NVVRFY-NAFEDKNSVYIVMELCEGGELLDRILARKD 203

  Fly   112 GAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTL 176
            ..::||:||.::.::.......|.|.:.|||:||||.|:.:|:.::.||.||||.:.........
plant   204 SRYSERDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKATDFGLSDFIKPGKKF 268

  Fly   177 QTPCYTPYYVAPEVL----GPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRT 237
            .....:.||||||||    |||.     |:||:||:.||::||..||:..    ...|:...:..
plant   269 HDIVGSAYYVAPEVLKRRSGPES-----DVWSIGVISYILLCGRRPFWDK----TEDGIFKEVLK 324

  Fly   238 GQYDFPDPEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWIAQYNAVPQTPLCTGRMLKEAE 302
            .:.||....|..:|.:|||.:|.:|..||..||.....:|:.|:.:.....:.|:... :|....
plant   325 NKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVREGGDASEIPIDIS-VLNNMR 388

  Fly   303 E--TWPEVQEEMTRSLATMRVDYDQM-----QIKALDKSNNPLLTKRRKKIEEMELYMA 354
            :  .:..:::...|:||| .:|.:::     |..|:|...|.:::     :|||...:|
plant   389 QFVKFSRLKQFALRALAT-TLDEEELADLRDQFDAIDVDKNGVIS-----LEEMRQALA 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_001188547.1	STKc_MAPKAPK	18..280	CDD:270991	88/273 (32%)
MAPk-Ak2	NP_001188547.1	S_TKc	25..281	CDD:214567	87/267 (33%)
CPK16	NP_179379.1	STKc_CAMK	107..367	CDD:270687	88/272 (32%)
		S_TKc	108..368	CDD:214567	88/272 (32%)
		PTZ00184	404..549	CDD:185504	12/44 (27%)
		EFh	415..476	CDD:238008	8/32 (25%)
		EFh	496..550	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24349
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100