Protein Alignment MAPk-Ak2 and Mapkapk5

DIOPT Version :10

• Sequence 1: NP_524769.1
• Gene: MAPk-Ak2 / 44573
• FlyBaseID: FBgn0013987
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_001157515.1
• Gene: Mapkapk5 / 498183
• RGDID: 1564113
• Length: 473
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 144/363 - (39%)
• Similarity: 210/363 - (57%)
• Gaps: 40/363 - (11%)

  Fly    11 KTTPLTDDY-VTSNTVLGYGINGKVVQCTHRRTQQNYALKVLLDSERARREVDLHWRVSGCRYIV 74
            |.|.:.::| :.....||.||:|.|..|..:.||:.:|||:|||..:||.||.||...:....||
  Rat    12 KETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHSNIV 76

  Fly    75 NIIDVYENTFK------DRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYL 133
            .||:|:.|:.:      .|..||:|||.|||||||.||.....  |||::|:|:..:|..|:.:.
  Rat    77 EIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRH--FTEKQASQVTKQIALALQHC 139

  Fly   134 HSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYVAPEVL------- 191
            |..:||||||||||||:.....:|.:||.||||||  .....|.||.:|||||||:||
  Rat   140 HLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAK--VDQGDLMTPQFTPYYVAPQVLEAQRRHQ 202

  Fly   192 -----------GPEKYDKSCDIWSLGVVMYIIMCGFPPFYS-NHGLAISPGMKNRIRTGQYDFPD 244
                       .|..|:||||:|||||::|:::||:||||| :|...|...|:.:|.||.::||:
  Rat   203 KEKSGLIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFPE 267

  Fly   245 PEWTNVSQAAKDLIKGMLNVDPSKRLRIQDVISNKWI----AQYNAVPQTPLCTGRMLKEAEETW 305
            .||:.:|:.|||:::.:|.|.|.:||.|:.|:.:.|:    |..|.:|...|...:.:...
  Rat   268 EEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLMMDKAVVAG---- 328

  Fly   306 PEVQEEMTRSLATMRVDYDQMQIKALDKSNNPLLTKRR 343
              :|:.....||.||:...::.:|.|...|||:|.||:
  Rat   329 --IQQAHAEQLANMRIQDLKVSLKPLHSVNNPILRKRK 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_524769.1	STKc_MAPKAPK	18..280	CDD:270991	124/287 (43%)
Mapkapk5	NP_001157515.1	STKc_MAPKAPK5	15..304	CDD:271073	124/292 (42%)