Protein Alignment MAPk-Ak2 and Pnck

DIOPT Version :10

• Sequence 1: NP_524769.1
• Gene: MAPk-Ak2 / 44573
• FlyBaseID: FBgn0013987
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: XP_006229634.1
• Gene: Pnck / 29660
• RGDID: 69249
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 106/291 - (36%)
• Similarity: 162/291 - (55%)
• Gaps: 29/291 - (9%)

  Fly     1 MLSLQNQRQPKTTPLTDDYVTSNTV---LGYGINGKVVQCTHRRTQQNYALKVL----LDSERA- 57
            ||.|:.|        |:|..:...:   ||.|...:|:....|.:....|||.:    |..:.|
  Rat     4 MLLLKKQ--------TEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEAL 60

  Fly    58 -RREVDLHWRVSGCRYIVNIIDVYENTFKDRKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQ 121
             ..|:.:..|:|... ||.:.||:|:.    ..|.:.||.:.|||||.||.::  |::||::|:.
  Rat    61 VENEIAVLRRISHPN-IVALEDVHESP----SHLYLAMELVTGGELFDRIMER--GSYTEKDASH 118

  Fly   122 IMHEICAAVDYLHSRDIAHRDLKPENLLYTTTQPNATLKLTDFGFAKETFTSYTLQTPCYTPYYV 186
            ::.::..||.||||..|.|||||||||||.|...::.:.::|||.:| ......|.|.|.||.||
  Rat   119 LVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSK-IQAGNMLGTACGTPGYV 182

  Fly   187 APEVLGPEKYDKSCDIWSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVS 251
            |||:|..:.|.|:.|:|:|||:.||::||:||||...    .|.:.::|....|:|..|.|.::|
  Rat   183 APELLEQKPYGKAVDVWALGVISYILLCGYPPFYDES----DPELFSQILRASYEFDSPFWDDIS 243

  Fly   252 QAAKDLIKGMLNVDPSKRLRIQDVISNKWIA 282
            ::|||.|:.:|..||.||...|..:.:.||:
  Rat   244 ESAKDFIRHLLERDPQKRFTCQQALQHLWIS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPk-Ak2	NP_524769.1	STKc_MAPKAPK	18..280	CDD:270991	99/270 (37%)
Pnck	XP_006229634.1	STKc_CaMKI_beta	14..290	CDD:271071	100/273 (37%)