DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd3 and ASHR2

DIOPT Version :9

Sequence 1:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_849991.1	Gene:	ASHR2 / 816483	AraportID:	AT2G19640	Length:	398	Species:	Arabidopsis thaliana

Alignment Length:	418	Identity:	92/418 - (22%)
Similarity:	147/418 - (35%)	Gaps:	138/418 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 APQIKRGQRILTEKPF----AFVLKSQYRLERCDNC---LEATKVLKCSNCRYVSYCHRSCQMQA 89
            |..::.||.||.|.|.    ||...|......||:|   |.::...||.:|..||:|..:|
plant    28 AQSLRAGQVILRESPLLLYSAFPFLSSSVSPYCDHCFRLLASSAHQKCQSCSLVSFCSPNC---- 88

  Fly    90 WGQHKHECPFLKKVHPRVVPDAARMLCRLILRLEHGGDLIRGYYTEHGSRKF--RDLMSHYAEIK 152
            :..|   .|:               ||..:.||.....  ..:..:...|:.  |.|:|.|....
plant    89 FASH---TPW---------------LCESLRRLHQSSS--SAFSDQPSDRQVQARFLLSAYNLAA 133

  Fly   153 NDPMRLEHL------------------DS-----LHAVLTDMMAESPSTV-PNKTELMSIYGRLI 193
            ..|...:.|                  ||     ||::|:.:....|.:: |:.|  .::..:..
plant   134 ASPSDFQILLSLQGSGSSNGDPSCSAGDSAAAGFLHSLLSSVCPSLPVSISPDLT--AALLSKDK 196

  Fly   194 TNGFNILDA-----EMNSI-ATAIYLGVSITDHSCQPNAV------ATFEGN-ELHVHAIEDME- 244
            .|.|.:::.     |..|: |..||...|..:|.|.|||.      :..:|| ::.:..|.|:.
plant   197 VNAFGLMEPCSVSNEKRSVRAYGIYPKTSFFNHDCLPNACRFDYVDSASDGNTDIIIRMIHDVPE 261

  Fly   245 ----CLDWSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKC--------------------TDA 285
                ||.:..:.::|     :..|:|  |.|.|.|.|.|.:|                    .|.
plant   262 GREVCLSYFPVNMNY-----SSRQKR--LLEDYGFKCDCDRCKVEFSWSEGEEDENEIMEEMEDQ 319

  Fly   286 KESKEMLAALCPNRN--CGAGISVDRNNCPR--------CD--------AGISPKLRNAFNEAMT 332
            .|.:||..::..|..  ||.|:. |.:|.|.        |:        |.:.||..:|
plant   320 DEQEEMEDSVGENEEEVCGNGVD-DESNFPHAYFFVRYMCEKENCFGTLAPLPPKTHDA------ 377

  Fly   333 LTRHNLENMKDVAYLDVCKVCLDKQTGV 360
                     ..|...:||....:.:.||
plant   378 ---------SRVLECNVCGSVKEDEVGV 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	zf-MYND	60..97	CDD:280009	12/39 (31%)
Smyd3	NP_524768.2	TPR_12	377..440	CDD:290160
ASHR2	NP_849991.1	SET	<192..275	CDD:214614	19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	1	1.000	-	-		FOG0000637
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820