DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd3 and SDG37

DIOPT Version :9

Sequence 1:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_849969.2	Gene:	SDG37 / 816300	AraportID:	AT2G17900	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	463	Identity:	124/463 - (26%)
Similarity:	211/463 - (45%)	Gaps:	45/463 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 APQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVLKCSNCRYVSYCHRSCQMQAWGQHKHE 96
            |...:.|:.||::||:..|..:.....|||.|.:...:.|||.|:.|.||..|||...|..|:.|
plant    33 ARDFRPGEVILSQKPYICVPNNTSSESRCDGCFKTNNLKKCSACQVVWYCGSSCQKSEWKLHRDE 97

  Fly    97 CPF---LKKVHPRVVPDAARMLCRLILRLEHGGDLIRGYYTEHGSRKFRDLMSHYAEIKNDPMRL 158
            |..   |:|...:.|....|::.||.::.....:.:....|.........|:||.:||....|.|
plant    98 CKALTRLEKEKRKFVTPTIRLMVRLYIKRNLQNEKVLPITTTDNYSLVEALVSHMSEIDEKQMLL 162

  Fly   159 EHLDSLHAVLTDMMAESPSTVPNKTELMSIYGRLITNGFNILDAEMNSIATAIYLGVSITDHSCQ 223
            .   :..|.|.:::.:.||.  :..|:...:.:...|..:|.|:|:......::..|||.:|||.
plant   163 Y---AQMANLVNLILQFPSV--DLREIAENFSKFSCNAHSICDSELRPQGIGLFPLVSIINHSCS 222

  Fly   224 PNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKCT----- 283
            ||||..||.....|.|::::.  ..|:|.||||:...:...|:..|||.|.|.|.|::|:
plant   223 PNAVLVFEEQMAVVRAMDNIS--KDSEITISYIETAGSTLTRQKSLKEQYLFHCQCARCSNFGKP 285

  Fly   284 -DAKESKEMLAALCPNRNCGAGISVDRNN----CPRCDAGISPKLRNAFNEAMTLTRHNLENMKD 343
             |.:||..:....|.|..|...:..|...    |.:|      .|..:..|...|.    .::|.
plant   286 HDIEESAILEGYRCANEKCTGFLLRDPEEKGFVCQKC------LLLRSKEEVKKLA----SDLKT 340

  Fly   344 V--------------AYLDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEAAIEVGKWSDALDYGQR 394
            |              |.:::.|.....|..::|..::..::|.:...:..::|..|.:||:|.:.
plant   341 VSEKAPTSPSAEDKQAAIELYKTIEKLQVKLYHSFSIPLMRTREKLLKMLMDVEIWREALNYCRL 405

  Fly   395 LLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEALHHLEEAQRILTVTHGRDHRLLTEQLYML 459
            ::|.:::.:...:||:||.....||::...|.:|||:..|.:|..||.::||.....:.| |...
plant   406 IVPVYQRVYPATHPLIGLQFYTQGKLEWLLGETKEAVSSLIKAFDILRISHGISTPFMKE-LSAK 469

  Fly   460 VLQARQEA 467
            :.:||.||
plant   470 LEEARAEA 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	zf-MYND	60..97	CDD:280009	15/36 (42%)
Smyd3	NP_524768.2	TPR_12	377..440	CDD:290160	18/62 (29%)
SDG37	NP_849969.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I3490
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41491
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1631
OMA	1	1.010	-	-		QHG55359
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	1	1.000	-	-		FOG0000637
OrthoInspector	1	1.000	-	-		oto3678
orthoMCL	1	0.900	-	-		OOG6_101699
Panther	1	1.100	-	-	LDO	PTHR12197
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X437
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840