back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd3 and smyd2a

DIOPT Version :9

Sequence 1:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001013568.1	Gene:	smyd2a / 541423	ZFINID:	ZDB-GENE-050320-126	Length:	435	Species:	Danio rerio

Alignment Length:	448	Identity:	109/448 - (24%)
Similarity:	203/448 - (45%)	Gaps:	55/448 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVL-KCSNCRYVSYCHRSCQM 87
            |.:.|| .....|.|..:.....:|:||....|..||:.|....:.| ||..|:...||:..||.
Zfish    17 KGRGLK-AIKHFKVGDLVFACPAYAYVLTVNERGGRCECCFTRKEGLSKCGKCKQAYYCNVECQR 80

  Fly    88 QAWGQHKHECPFLKKVHPRVVP-DAARMLCRLILRLEHGGDLIRGYYTEHGSRK----FRDLMSH 147
            ..|..||.||..:........| :..|::.|:||:.:|        .||....:    .|:|.:|
Zfish    81 GDWPMHKLECSAMCAYGENWCPSETVRLVARIILKQKH--------QTERTPSERVLTLRELEAH 137

  Fly   148 YAEIKNDPMRLEHLD--SLHAVLTDMMAESPSTVPNKTELMSIYGRLITNGFNILDAEMNSIATA 210
            ..::.|:...:...|  :||...:..:     ..|:...|..:..::..|||.|.|.|::.:.:|
Zfish   138 LDKLDNEKNEMNDTDIAALHHFYSRHL-----DFPDNAALTELIAQVNCNGFTIEDEELSHLGSA 197

  Fly   211 IYLGVSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYF 275
            ::..|::.:|||.||.:.|::|....|.|::::.  ...:||.||||||...|.|...||:.|:|
Zfish   198 LFPDVALMNHSCSPNVIVTYKGTVAEVRAVQEIN--PEEEIFNSYIDLLYPTEDRIERLKDSYFF 260

  Fly   276 LCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNCPRCDAGISPKLRNAFNEAMTLTRHNLEN 340
            .|.|.:||...:.:..:..                   |....|.|: .....:.:...|:.:|.
Zfish   261 NCDCKECTSKSKDEAKMEI-------------------RQKLSIPPE-EEEIKQMVIYARNVIEE 305

  Fly   341 MKDVAY-------LDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPG 398
            .:...:       |::|::.::|...:|...||:.:..:..|....:.:..|..|:.||::::..
Zfish   306 FRRAKHYKTPSELLEICELSMEKMGAIFAETNVYMLHMMYQAMGVCLYMQDWDGAMKYGEKIIHP 370

  Fly   399 FRKYHGPWNPLLGLLHMKLGKIQLYEGHSK--EALHHLEEAQRILTVTHGRDHRLLTE 454
            :..::.|::..:..:::|||:  ||.|..|  :.:..|::|..|:.:.||:||..:.|
Zfish   371 YSVHYPPYSLNVASMYLKLGR--LYLGLEKRTQGVKALKKALAIMDIAHGKDHPYIDE 426

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.