DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd3 and SmydA-1

DIOPT Version :9

Sequence 1:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_610944.1	Gene:	SmydA-1 / 36581	FlyBaseID:	FBgn0033917	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	86/397 - (21%)
Similarity:	125/397 - (31%)	Gaps:	145/397 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 CDNCLEATKVLKCSNCRYVSYCHRSCQMQAWGQHKHECPFLKKVH-------------------- 104
            |..|.|.|| .|||||..||||....|.|.|..||..|...|..|
  Fly     4 CHVCEEPTK-NKCSNCNQVSYCSVQHQKQDWKVHKPSCHPFKIAHNEQLGRHLVATRTIKPYEIV 67

  Fly   105 --------------------------------------PRVVP-----DAARMLCRL-------I 119
                                                  |...|     |..:..|.|       :
  Fly    68 LKEAPLVRGPAQISAPVCLGCLNGIEAEDHIECEQCGWPLCGPECKSLDEHKAECGLTKDRGQKV 132

  Fly   120 LRLEHGGD------------LIRGYYTEHGSRKFRDLMSHYAEIKNDPMRLEHLDSLHAVLTDMM 172
            ...|.||.            |:.|..:...:.||:|              ||.|:|.........
  Fly   133 NVQEFGGPHPLYTCLSTVRCLLIGETSTEKASKFQD--------------LESLESTRRGSNQWK 183

  Fly   173 AESPST---VPN--KT------ELMSIYGRLITNGFNILDAEMNSIATAIYLGVSITDHSCQPNA 226
            |:..|.   :|.  ||      |:|...|.|..||..:...:.:.:  |::...|.|::||.||.
  Fly   184 ADLVSIGQFIPKFFKTQKFTEEEIMKAVGALQINGHEVPTTDPSHV--AVFYTASFTENSCLPNL 246

  Fly   227 VATFEGNELHVHAIEDMECLDW--------SKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKCT 283
            ..:|..|.         .|:.|        :.:.|.|.|.:.....|:..|.:...|.|.|.:|.
  Fly   247 AKSFNKNG---------HCILWAPREIKKNAHLSICYSDAMWGTADRQRHLMQTKLFKCACERCV 302

  Fly   284 DAKESKEMLAAL-CPNRNCGAGISV-----DRNNCPRCDAGISPKLRNAFNEAMTLTRHNLENMK 342
            |..|.....:|: |.:|.|| |:.:     :.|...||        |....:   :.:|.:|.:.
  Fly   303 DVTELDTNYSAIKCEDRQCG-GLMLPTKADEWNGSWRC--------RECHKQ---VQKHYVERIL 355

  Fly   343 DVAYLDV 349
            :.|..|:
  Fly   356 ERAGKDI 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	zf-MYND	60..97	CDD:280009	19/36 (53%)
Smyd3	NP_524768.2	TPR_12	377..440	CDD:290160
SmydA-1	NP_610944.1	zf-MYND	4..40	CDD:280009	19/36 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4564
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.770