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Protein Alignment Smyd3 and Smyd2

DIOPT Version :9

Sequence 1:	NP_524768.2	Gene:	Smyd3 / 44554	FlyBaseID:	FBgn0011566	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_081072.1	Gene:	Smyd2 / 226830	MGIID:	1915889	Length:	433	Species:	Mus musculus

Alignment Length:	483	Identity:	116/483 - (24%)
Similarity:	210/483 - (43%)	Gaps:	97/483 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CSS-KSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVL-KCSNCRYVSYCHR 83
            ||: |.:.|:...| ...|..:.:...:|.||....|...|:.|....:.| ||..|:...||..
Mouse    13 CSAGKGRGLRALRP-FHVGDLLFSCPAYACVLTVGERGHHCECCFARKEGLSKCGRCKQAFYCDV 76

  Fly    84 SCQMQAWGQHKHECPFL----------------------KKVHPRVVPDAARMLCRLILRLEHGG 126
            .||.:.|..||.||..:                      :|:||...| :.::|.
Mouse    77 ECQKEDWPLHKLECSSMVVLGENWNPSETVRLTARILAKQKIHPERTP-SEKLLA---------- 130

  Fly   127 DLIRGYYTEHGSRKFRDLMSHYAEIKNDPMRLEHLD--SLHAVLTDMMAESPSTVPNKTELMSIY 189
                          .|:..||..::.|:...|...|  :||...:..:     ..|:.:.|:.::
Mouse   131 --------------VREFESHLDKLDNEKKDLIQSDIAALHQFYSKYL-----EFPDHSSLVVLF 176

  Fly   190 GRLITNGFNILDAEMNSIATAIYLGVSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFIS 254
            .::..|||.|.|.|::.:.:||:..|::.:|||.||.:.|::|....|.|::::...|  ::|.|
Mouse   177 AQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIHPGD--EVFTS 239

  Fly   255 YIDLLNTPEQRRLDLKEHYYFLCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNCPRCDAGI 319
            |||||...|.|...|::.|:|.|.|.:||...:.|             |.:.|.:.:
Mouse   240 YIDLLYPTEDRNDRLRDSYFFTCECRECTTKDKDK-------------AKVEVRKLS-------- 283

  Fly   320 SPKLRNAFNEAMTLTRHNLENMKDVAY-------LDVCKVCLDKQTGVFHPLNVWYVKTLDAAFE 377
            ||....|..:.:...|:.:|..:...:       |::|::..:|.:.||...||:.:..:..|..
Mouse   284 SPPQAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMG 348

  Fly   378 AAIEVGKWSDALDYGQRLLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEALHH--LEEAQRI 440
            ..:.:..|..||.|||:::..:.|::..::..:..:.:|||:  ||.|...:|...  |::|..|
Mouse   349 VCLYMQDWEGALKYGQKIIKPYSKHYPVYSLNVASMWLKLGR--LYMGLENKAAGEKALKKAIAI 411

  Fly   441 LTVTHGRDHRLLTEQLYMLVLQARQEAH 468
            :.|.||:||..::|      ::...|:|
Mouse   412 MEVAHGKDHPYISE------IKQEIESH 433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.