Protein Alignment lola and LOC1277065

DIOPT Version :10

• Sequence 1: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: XP_061506393.1
• Gene: LOC1277065 / 1277065
• VectorBaseID: AGAMI1_001094
• Length: 892
• Species: Anopheles gambiae
• Alignment Length: 969
• Identity: 243/969 - (25%)
• Similarity: 343/969 - (35%)
• Gaps: 285/969 - (29%)

  Fly     5 QQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHP 69
            ||:||||||||...||||.|||.||:|||.||||||:.|:||||||||||.||.:|......:||
Mosquito     5 QQYCLRWNNHQPNFISVFSTLLHNESLVDVTLAAEGRQLQAHKVVLSACSSYFQSLFTANPCQHP 69

  Fly    70 IFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHH 134
            |.|||||:|.:|:.|:|:||.||||:|.:||..:||.||.|:||||         |..|::|...
Mosquito    70 IVILKDVQYNDLKTMVDFMYYGEVNVSTEQLPQVLKTAEMLKIKGL---------AEMPDASAVC 125

  Fly   135 RGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDN----- 194
            : ..||.....|..:.|.:..|.|.|.   :.||.|......:::::.:::..:......
Mosquito   126 K-ADLSKLDPSELIQAANVIPGAAGDA---IWGSAESQQQAQQQQQQQQQQQQQQQQQQQQQQQQ 186

  Fly   195 --------SNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAA----------GTSSQASS 241
                    .:....|.....|.:.||| ..|..|...||.:|  |||          |:.|.:|.
Mosquito   187 QAQHQQQYQHQQQQQQQQQQQQLHQQT-QQLRRSPSPTTNMS--PAARRKRLRKTSTGSGSISSE 248

  Fly   242 TQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQ 306
            ..|||............:|:  ...||.|:.|:|:||.||....|||.|           |.|.|
Mosquito   249 RLQQQQQQQAAAAAAAVAAQ--QQAAAVAAAAAAAAAAQQQAEEQQQQQ-----------QQQQQ 300

  Fly   307 GGAQG------------VQGDDEDIDEGSAVGGPNS-ATGPNPASASASAVHAG----VVVKQLA 354
            .||..            :|...::|..|:|..|..: |.|...|.|:|:|..||    ::.:..:
Mosquito   301 HGAGADPSTINLVPHLHIQQQVDNISYGTATTGHGALALGAAAAVAAAAAAAAGNNIRIIKESPS 365

  Fly   355 SVVDKSSSNHKHKIKDNSVSSVGSEM--VIEPKAEYDDDAHDENVEDLTLDEEDMTME------- 410
            |.||:    .:|:....||...|..|  :|:             .|||:...:.:.|:
Mosquito   366 SDVDQ----QQHESSQESVDETGHHMPSIIK-------------TEDLSGVAQTIPMDISTTPTA 413

  Fly   411 -ELDQTAGTSQGGEGS--SQTYATWQHDRSQDELGLMAQDAQQRDPQASKQDKGEQTEGAQDEFE 472
             .:.|:.....||:.:  ...|:.:.....|..|||..|..||:..|..:|.:.:|....|...:
Mosquito   414 VNITQSQSQHTGGQWTVIDTNYSRFGIAPIQTNLGLQQQQQQQQQQQQHQQQQVQQQHHQQTSQQ 478

  Fly   473 LDDCLLESNDIVITQNKDGFVLHVKKLGNITAAKLEENQAVAQQQGQAAVTVTGPAGQPTPTITE 537
            .........|             .:.||  :|.....|.|.:...|..|....|..|.     ..
Mosquito   479 QQQHQQHQGD-------------SQSLG--SAGNGANNPANSGATGGGAGASAGSGGN-----NG 523

  Fly   538 LLNAAAASHSE---PKPTLTTLTSTPIKLPSSECELINIKKIIPATTTIATHHPHTSSTIIHPHH 599
            .|..|:|::|.   |:||      ||:::                     ..||.:.
Mosquito   524 GLAGASATNSNATTPQPT------TPVQI---------------------YQHPFSP-------- 553

  Fly   600 IIQHVSQEPHHQEHHQQHQTIHIEEVPQTSQQHHQQQHHHQLQT---VQPTHTQVQSII-----T 656
              |.:|..|:...:..|...:.....||....          ||   |..|.|..||.:     |
Mosquito   554 --QIISVNPNSMVNSYQSSNLSTPTSPQAGSD----------QTAGLVYSTGTPNQSPLGTTTAT 606

  Fly   657 AHPGQTINLVGLRNVQLADSKPIASRIRYSRGK-------------IIGPTVQNLQIVETHEPIQ 708
            |.........|......|.....|.......|.             ..|.|||        :|::
Mosquito   607 ASGTNASGNGGNGAAAAAGGNGAAGGNGAGAGTAGSGAGAAGGAAGAAGATVQ--------QPVK 663

  Fly   709 HQHHELSDGTK--------------------------------------YEISEIDLNN-----P 730
            .:......|.:                                      |.||...:.|     |
Mosquito   664 RKRSVNPQGDENFLRALEAVRFGGIGFCKAARLYGVNNRTLWLEYKKRGYPISRPSIKNRIKLEP 728

  Fly   731 NASAAIISDLVKYAEIDDIELPDGTKIGIGFAPSEITEHMQTSGGETHITTIEHEP------QEL 789
            |.|.                           .|:..|.....:....|..|....|      |:.
Mosquito   729 NISP---------------------------PPTATTPPGDENASLEHYDTALSSPALNMSLQQQ 766

  Fly   790 QTVHQHEQTQQTHHIHAGQLQTHHIQTVVQSSSGQQQHDQQQHHQHHSIELQDDDGVET 848
            |...|.:|.||.|       ||:..|.|..:...|||..|.|.||.     |...|.:|
Mosquito   767 QQQQQQQQVQQQH-------QTNQQQQVTAAQQQQQQQQQTQQHQQ-----QQQQGTDT 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	50/82 (61%)
		C2H2 Zn finger	905..925	CDD:275368
		zf-H2C2_5	935..957	CDD:404746
		C2H2 Zn finger	935..955	CDD:275368
LOC1277065	XP_061506393.1	None