Protein Alignment lola and ttk

DIOPT Version :10

• Sequence 1: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: XP_061497449.1
• Gene: ttk / 1274194
• VectorBaseID: AGAMI1_010022
• Length: 885
• Species: Anopheles gambiae
• Alignment Length: 1021
• Identity: 232/1021 - (22%)
• Similarity: 376/1021 - (36%)
• Gaps: 351/1021 - (34%)

  Fly     5 QQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHP 69
            |:|||||||||:.|::|||.||.:||.:|.|||.||:.|||||:|||||||||..|.....:|||
Mosquito     4 QRFCLRWNNHQTNLLAVFDQLLHDETFIDVTLAVEGQHLKAHKMVLSACSPYFQQLFVSHPEKHP 68

  Fly    70 IFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGL---SDNR----TGGGVAPK 127
            |.||:||.:::::.::|:||||||::.||:|||.|:.||||:||||   :|::    :|...|..
Mosquito    69 IVILRDVPFKDMKCLLDFMYRGEVSVDQDRLAAFLRVAESLRIKGLTEVNDDKPNAPSGSASATA 133

  Fly   128 PESSGH--HRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMEND 190
            ..|:|.  ..|.:.:||.|...|.........:..:||.||                   .:::|
Mosquito   134 TNSAGSAASSGAQATGATTTTNTVPNATVQKNSSGSSGMVS-------------------QVDDD 179

  Fly   191 AHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASS--TQQQQP-LTSTN 252
            ..|..:.                         |...::..|.|.:|.||..  .:...| |:||.
Mosquito   180 EDDRCSP-------------------------VPNSIAVAPNAASSGQAQGGHLKPLPPLLSSTG 219

  Fly   253 VTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTE-NVQAQSQGGAQGVQGDD 316
            :..::.|..|...  ..:|.||.||.||           |:..:.|. :.|.:.:|..:.:.|.|
Mosquito   220 IVTRSHSNSLLQQ--GGSSAASGSAMVQ-----------TNPLLGTALSQQKRKRGRPRKLSGSD 271

  Fly   317 --EDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSE 379
              |...||:.||| ..|.|....|:|..     ::..::||....:|.:...:::..|..:...:
Mosquito   272 AGEGETEGNFVGG-GGAPGEEYDSSSMD-----IMDVKIASSGASNSGDDDQQLRIVSSRTDDDD 330

  Fly   380 MVIEPKAEYDDDAHDENVEDLTLDE--EDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELG 442
            .::..|||..||..||.::| ..||  :|:.:|..|:..|||...:.|.:. .|...|.:.:..|
Mosquito   331 TLMHEKAEQLDDEDDEVMDD-EADELVDDVDLEAGDEPRGTSPSLDESMED-TTGNMDGTTNNNG 393

  Fly   443 LMAQDAQQRDPQ---------ASKQDKGEQTEG----AQDEFELDD-C-------LLESNDIVIT 486
            ...:..:|...|         |||:.:....|.    ::|.|..|| |       ..|..|.:..
Mosquito   394 NTNRSGRQHQKQGTAAAKPSRASKRSRTRNNENSLSDSKDSFAEDDKCNKLDGTGAGEEEDDIED 458

  Fly   487 QNKDGFVLHVKKLGNITAAKLEENQAVAQQQGQ------------AAVTVTG-----PAGQPTPT 534
            ...||..|:         :.|.|.|.:..:..:            .||..|.     |..||.|.
Mosquito   459 DQYDGRELN---------SSLMEPQLLLDEYDEPVEFKFDPRTDSGAVDSTSNSNYLPPLQPKPG 514

  Fly   535 ITELLNAAAASHSEPKPTLTTLTSTPIKLPSSECELINIKKIIPATTTIATHHPHTSSTIIHPHH 599
                |..|:.|.....|.::.:.:|.:::|          |:.|
Mosquito   515 ----LKIASTSGGARMPQISVVPTTALQIP----------KLAP--------------------- 544

  Fly   600 IIQHVSQEPHHQEHHQQHQTIHIEEVPQTSQQHHQQQHHHQLQTVQPTHTQVQSIITAHPGQTIN 664
                                                                   :||..|.|.:
Mosquito   545 -------------------------------------------------------LTASGGGTSS 554

  Fly   665 LVGLRNVQLADSKPIASRIRYSRGKIIGPTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLNN 729
            .:|      ..|...:|...:.|.:::.|...|  .:.|.:.|.:                :|||
Mosquito   555 FLG------GGSNNKSSVKLHKRARLMTPKKPN--GMTTTQTILN----------------NLNN 595

  Fly   730 PNASAAIISDLVKYAEIDDIELPDGTKIGIGFAPSEITEHMQTSGGETHITTIEHEPQELQTVHQ 794
             |.:.::||                            |.:..:.|....||.|..|
Mosquito   596 -NLNESLIS----------------------------TSNTASGGSSLCITGIGSE--------- 622

  Fly   795 HEQTQQTHHIHAGQLQTHHIQTVVQSSSGQQQHDQQQHHQHHSIELQDDDGVETITPEELGMHDS 859
                  .:.:.:|        :|::|||.:.                               :.:
Mosquito   623 ------MYDMFSG--------SVLRSSSPRS-------------------------------NSN 642

  Fly   860 SKSYTILTTRPMKEESEHDPSGMTYELSLSDSSLGPCDD-----PESRYVCRHCGKKYRWKSTLR 919
            |.|        :|..|.:|....|::.::.|.:.|...|     .:..|.|:.|.:.|...|...
Mosquito   643 SPS--------VKGGSGNDSGSRTHKYAVIDDTEGSVRDFCTKEGDHVYRCKVCARVYTHISNFC 699

  Fly   920 RH------ENVECGGKEPCHPCPYCSYKAKQRGNLGVHVRKHHPEK 959
            ||      .||:      .:|||:|..:..::.|:..||:..|.::
Mosquito   700 RHYVTSHKRNVK------VYPCPFCLKEFTRKDNMTAHVKIIHKQE 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	47/82 (57%)
		C2H2 Zn finger	905..925	CDD:275368	7/25 (28%)
		zf-H2C2_5	935..957	CDD:404746	6/21 (29%)
		C2H2 Zn finger	935..955	CDD:275368	6/19 (32%)
ttk	XP_061497449.1	None