Protein Alignment lola and fru

DIOPT Version :10

• Sequence 1: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: XP_061511040.1
• Gene: fru / 1272191
• VectorBaseID: AGAMI1_010944
• Length: 1004
• Species: Anopheles gambiae
• Alignment Length: 1202
• Identity: 234/1202 - (19%)
• Similarity: 340/1202 - (28%)
• Gaps: 518/1202 - (43%)

  Fly     4 DQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKH 68
            |||:|||||||||.|.:|..|||::|.|.|.|||.|...:|||:.:||||||||..:..|....|
Mosquito    62 DQQYCLRWNNHQSNLTTVLTTLLQDEKLCDVTLACEKGMVKAHQAILSACSPYFEQIFVENKHPH 126

  Fly    69 PIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGH 133
            ||..|:||:..|:||::|:||:||||:.|..|...||.||||:::||:            |||..
Mosquito   127 PIIYLRDVEVNEMRALLDFMYQGEVNVGQHNLQNFLKTAESLKVRGLT------------ESSAD 179

  Fly   134 HRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSS 198
            ............|:.:.:|.......:.|.:.|.:...|||                 ::|:|::
Mosquito   180 RYSADTDSKLRSERIRDSRDERDSLPNASSNNSNNNNNSSS-----------------NNNNNNN 227

  Fly   199 VLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTS----SQASSTQQQQPLTSTNVTKKTES 259
            .:.:..:|.|                  |..||.....    .|....||||
Mosquito   228 TISSNNNNNS------------------LHHGPLRDKELTEHEQLERLQQQQ------------- 261

  Fly   260 AKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQ----------------GG 308
                                ||.|..|||..::....:.::..:|.|                ||
Mosquito   262 --------------------QQTHHQQQQHPSSHQQQSQQHPSSQHQQPTHQTHHHHHHHQHGGG 306

  Fly   309 AQGVQGDDEDIDEGSAVGGPNSATGP--NPA-SASASAVHAGVV-VKQLASVVDKSSSNHKHKIK 369
            ..|          |...||...:.||  .|: |||...:.:.:| .:...:..|:..|..::|.|
Mosquito   307 GGG----------GGGGGGGGGSAGPVQQPSRSASIDLMQSALVDERDYLAAEDREISTVENKKK 361

  Fly   370 -------DNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQ 427
                   |||..|..|.|                                    ...|||..|
Mosquito   362 RKLSTTCDNSSPSTPSLM------------------------------------NERQGGYES-- 388

  Fly   428 TYATWQHDRSQDELGLMAQDAQQRDPQASKQDKGEQTEGAQDEFELDDCLLESNDIVITQNKDGF 492
                                      |||.....:|:...:|||::
Mosquito   389 --------------------------QASSHSSFKQSPKPEDEFKV------------------- 408

  Fly   493 VLHVKKLGNITAAKLEENQAVAQQQGQAAVTVTGPAGQPTPTITELLNAAAASHSEPKPTLTTLT 557
                                      .:...|...||.|...|.:.|......||     |::..
Mosquito   409 --------------------------SSPAPVHPLAGHPLSGIKQELPELPVRHS-----LSSEL 442

  Fly   558 STPIKLPSSECELINIKKIIPATTTIATHHPHTSSTIIHPH-HI--IQHVSQEP----------- 608
            ..|:|:|....|:                   ::|..:.|| |:  ::|.|:.|
Mosquito   443 MQPLKMPLYADEM-------------------SASIGLEPHAHLNHLRHKSKHPIPINMNADDMN 488

  Fly   609 ---------------------HHQEHHQQHQTIHIEEVPQTSQQHHQQQ--HHHQLQTVQPTHTQ 650
                                 .|.:|........:..:...|:.||.:.  |||.|    .:...
Mosquito   489 NILAPGNMGSLNESGDSDAHLSHPDHPDNIDGDRMLRLAMASRHHHHRAGLHHHDL----ASGVV 549

  Fly   651 VQSIITAHPG-----------QTINLVGLR-------NVQLADSKPIASRI---------RYSRG 688
            |.:::.|..|           :|:...|:.       ..:.|....:.|.|         |...|
Mosquito   550 VNAVLAAGGGGGGGSGCVNGSRTVGAGGMAGGGSDGPEYEGAGRGGVGSGIGGGGGGGGGRAGGG 614

  Fly   689 KIIGPTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLN----NPNASAAIISDL--------- 740
              :|.|.     .|..:..:..||..::....|.|.....    .|.|:||.:..|
Mosquito   615 --VGATG-----AEKQQQNRSNHHRTTEQADREASVCAAGGGGVGPAAAAAGVGGLGCDSGAAAA 672

  Fly   741 ----------VKYAEIDDIELPDGTKIGIGFAPSEITEHMQTS---------------------- 773
                      ........:.||.|   |.......:.||.:.:
Mosquito   673 AAAAAAAAAAASMLGFSGVPLPLG---GSSSLVESLVEHHRLAASLGGGAVGGGSGAGGGAGSSG 734

  Fly   774 ------------GGETHITTIEHEPQELQTVHQHEQTQQTHHIHAGQLQTHHIQTVVQSSSGQQQ 826
                        ||..|..:..|......|.|.|.|    ||     ...||
Mosquito   735 GSGGGLANGSPYGGGGHHLSHHHGGAGAATGHHHHQ----HH-----AAPHH------------- 777

  Fly   827 HDQQQHHQHHSIELQDD--DGVETIT----------PEELGMHDSSKSYTILTTRPMKEESEHDP 879
            |..||.|...:.....|  .||....          |:..|........::.:|.|....|....
Mosquito   778 HSLQQQHASSAFNSAGDARSGVAVAAALNTGGGGPPPDGSGSGSRCSKPSVTSTTPPTPASLSSS 842

  Fly   880 SGMTYELSLSDSSLGPC-------------------DDPE------------------------- 900
            |..    |.|.||...|                   .||.
Mosquito   843 SSS----SSSASSTSLCGGNGGGGGAGASGGGFLITGDPSDTIGAGGGGAGGPLRGSSGGAGGGS 903

  Fly   901 -------------------------------------SRYVCRHCGK--KYRWKSTLRRHENVEC 926
                                                 :.|.|..|.|  ..||     .|.|:.
Mosquito   904 SGGGGNGGTSGGGSSTTRRDHNIDYSSLFIQLTGTFPTLYSCVSCHKTVSNRW-----HHANIH- 962

  Fly   927 GGKEPCHPCPYCSYKAKQRGNLGVHVRKHHPE 958
              :...|.||.|..|..:|.|:..|.:..|||
Mosquito   963 --RPQSHECPVCGQKFTRRDNMKAHCKVKHPE 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	42/82 (51%)
		C2H2 Zn finger	905..925	CDD:275368	7/21 (33%)
		zf-H2C2_5	935..957	CDD:404746	7/21 (33%)
		C2H2 Zn finger	935..955	CDD:275368	7/19 (37%)
fru	XP_061511040.1	None