Protein Alignment lola and zbtb21

DIOPT Version :10

• Sequence 1: NP_788308.3
• Gene: lola / 44548
• FlyBaseID: FBgn0283521
• Length: 970
• Species: Drosophila melanogaster
• Sequence 2: NP_001090699.1
• Gene: zbtb21 / 100036678
• XenbaseID: XB-GENE-995449
• Length: 1030
• Species: Xenopus tropicalis
• Alignment Length: 1078
• Identity: 203/1078 - (18%)
• Similarity: 352/1078 - (32%)
• Gaps: 298/1078 - (27%)

  Fly    14 HQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQ-YDKHPIFILKDVK 77
            |.|:::|..:.....|...|..|....:..:|||.:|:|.|.||.:|..|: .:...:|.|....
 Frog    12 HASSMLSALNEERLKEEFCDVLLIVGDQKFRAHKNILAATSEYFQSLFTEKDNESQTVFQLDFCD 76

  Fly    78 YQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGA 142
            ......:::|:|...:.:.:..|||:.:...||.|..|::..:.....|.|         .:..|
 Frog    77 ADVFENVLNYIYSSSIFVEKSSLAAVQELGYSLGINFLTNIVSKTPQTPFP---------SIKNA 132

  Fly   143 YTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQ 207
            ...|:                |.|||::.|....:.|.:.:.|.:.:..||.|.
 Frog   133 EFKEE----------------DESGSQQRSVIVCQNRIEAQERDISHLHHDKSR----------- 170

  Fly   208 SILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASG 272
                         .|..:.|..|...|.......::....|.|        ..|..:|..:...|
 Frog   171 -------------PLKPSLLPQGKTHGNRPLMRLSEPPNSLLS--------ERKWRNSYVSDDQG 214

  Fly   273 ASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQG--VQGDDEDIDEGSAVGGPNSATGPN 335
            .|.|.          :.::|....:..::::..:.|..|  ::...|..::......|
 Frog   215 ISRSV----------KRKSTLPQKSFPSLESNDKPGISGCLLRNTSETFEKQMLASVP------- 262

  Fly   336 PASASASAVHAGVV-VKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVE- 398
            |:.:|:...::.:: .|:...:.::...|..:..|....||.||       ...:.|.....|:
 Frog   263 PSYSSSEYPYSSLIRGKESVPIKEEEEENVVYYSKVGLTSSAGS-------THQNTDRSGPLVKS 320

  Fly   399 ----DLTLD--------EEDMTMEELDQTAGTSQGGEGSSQTYA-TWQHDRSQDELGLMAQDAQQ 450
                .|::|        ..|.::|      |||...|..::..| ...|::|:.:|.|.|:|
 Frog   321 LLRRSLSMDSPVPAYSHSPDFSLE------GTSAMIENCNKAVAIAGFHNQSKTDLDLDARD--- 376

  Fly   451 RDPQASKQDKGEQTEGAQDEFELDDCLLES--NDIVITQNKDGFVLHVKKLGNITAAKLEENQAV 513
                           .||::..|....:.|  :.......||   :|:||         |.....
 Frog   377 ---------------NAQEKCNLKISFVSSKPHSRESIPEKD---VHIKK---------EPGSPP 414

  Fly   514 AQQQGQAAVTVTGPAGQPTPTITELLNAAAASHSEPKPTLTTLTSTPIK---------LPSSECE 569
            ::......||| |...||:       |......:|..|.:..:   |||         |||..
 Frog   415 SETSEIFRVTV-GDTSQPS-------NRDVPIKAEETPNIIKM---PIKRKLQADRRMLPSRR-- 466

  Fly   570 LINIKKIIPATTTI---ATHHPHTSSTIIHPHHIIQHVSQEPHHQEHHQQH-------------- 617
             :.:|..|....|:   |......||.......:....|:...:::...:|
 Frog   467 -VKMKSAISPDATLEEGALILDADSSDSESSRELYGEASESRQNKKFKCKHCLKIFRSTAGLNRH 530

  Fly   618 -QTIHIEEVPQTSQQHHQQQHHHQLQTVQPTHTQVQSIITAHP-----GQT----------INLV 666
             ...|..|.|......|::.|.:....   ||.|.|..|..:|     |.|          :::|
 Frog   531 VNMYHNPEKPYACDICHKRFHTNFKVW---THCQTQHGIVRNPSPASSGSTVLDDKFQRKLVDIV 592

  Fly   667 GLRNVQLADSKPIASRIRYSRGKIIGPTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLNNPN 731
            ..|.::    |.:..|:|  |||      |..| ..:..|.|.....|...:|   |....|:..
 Frog   593 REREIK----KALLFRLR--RGK------QGFQ-GSSGSPAQALRRSLRSRSK---SSYICNHCG 641

  Fly   732 ASAAIISDLVKYAEIDDIEL-PDGTKIGIGFAPS-------------------------EITEHM 770
            .|...:|...::.::...|. |.|:|.....|||                         |...|.
 Frog   642 KSYRFLSQFKQHCKMHPGEKNPFGSKENKPKAPSPPKSPVDNKEFFNCRLCNAKFPSFVEQGNHE 706

  Fly   771 QTSGGET--HITTIEHEPQELQTVHQHEQTQQTHHIHAGQLQTHHIQTVVQSSSGQQQHDQQQHH 833
            :.....|  ...::.....:|:..|:.:...:       :|.........:||....:|..:.|:
 Frog   707 RMCRNATLCPYCSLRFASPDLKNEHESKCEYK-------KLTCLECMRTFKSSFSIWRHQVEVHN 764

  Fly   834 Q-------HHSIELQDDDGVETITPEELGMHDSSKSYTILTTRPMKEE------SEH------DP 879
            |       :.|:.|.|.:|..........:.:|||..:.|.   :||:      |:|      |.
 Frog   765 QNTMAPTENFSLPLIDHNGEVRAASRMRSLAESSKVNSFLA---LKEDGIYSDSSDHMNFDSEDS 826

  Fly   880 SGMTYELSLSDS-----SLGPCDDPESR------------------YVCRHCGKKYRWKSTLRRH 921
            :.:..:||||..     ...|.||.|..                  :.|..|||.:.....|.||
 Frog   827 NCLPEDLSLSKQFHVQVKEEPADDMEDGSESNFGHKEDLSDSERGVWACEKCGKIFTVHKQLERH 891

  Fly   922 ENVECGGKEP--CHPCPYCSYKAKQRGNLGVHVRKHHP 957
            :.:.|..| |  ||   .|:...:....|..|.:.|.|
 Frog   892 QELLCTVK-PFICH---VCNKAFRTNFRLWSHFQSHMP 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lola	NP_788308.3	BTB_POZ_BAB-like	31..114	CDD:349624	22/83 (27%)
		C2H2 Zn finger	905..925	CDD:275368	7/19 (37%)
		zf-H2C2_5	935..957	CDD:404746	4/21 (19%)
		C2H2 Zn finger	935..955	CDD:275368	3/19 (16%)
zbtb21	NP_001090699.1	BTB_POZ_ZBTB21_ZNF295	12..123	CDD:349518	27/110 (25%)
		C2H2 Zn finger	514..535	CDD:275368	1/20 (5%)
		C2H2 Zn finger	637..657	CDD:275368	3/19 (16%)
		zf_C2H2_6	711..738	CDD:408245	3/26 (12%)
		C2H2 Zn finger	875..895	CDD:275370	7/19 (37%)
		C2H2 Zn finger	903..924	CDD:275370	5/23 (22%)