Protein Alignment Hnf4 and Rxrg

DIOPT Version :10

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_038947050.1
• Gene: Rxrg / 83574
• RGDID: 620046
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 160/484 - (33%)
• Similarity: 244/484 - (50%)
• Gaps: 97/484 - (20%)

  Fly    52 SASRTASSDESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSN------------ 104
            ||.||.|            |:.:...|...|:..|..|:.|..|.|......|
  Rat    51 SAPRTLS------------AVGTPLNALGSPYRVITSAMGPPSGALAAPPGINLVVPPSSQLNVV 103

  Fly   105 ---QSSENFALCNGNGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQS 166
               .|||:.....|....|:....|.|.||...:
  Rat   104 NSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKH------------------------------- 137

  Fly   167 PTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCF 231
              :|||||||::|||||..||:||||||:|::||:..||||..::|::||.:||:|:|||.:||.
  Rat   138 --ICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCL 200

  Fly   232 KAGMKKEAVQNERDR--------ISCRRTSNDDPDPGNGLSVISLVKAE---NESRQSKAGAAME 285
            ..|||:||||.||.|        ..|..|.::|      :.|..:::||   ....:|....::|
  Rat   201 VMGMKREAVQEERQRSRERAESEAECASTGHED------MPVERILEAELAVEPKTESYGDMSVE 259

  Fly   286 PNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSR 350
            .:.|:.::|        :|.:..:||.|||||||:||.|::|.|:|||.||||...|.|:...|.
  Rat   260 SSTNDPVTN--------ICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSH 316

  Fly   351 RSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRI-GARIIDELVTVMKDVGIDDTEFACIKALV 414
            ||:.::|.:||:....:.|..     :.:..:..| .:|::.|||:.|||:.:|.:|..|::|:|
  Rat   317 RSVSVQDGILLATGLHVHRSS-----AHSAGVGSIFDSRVLTELVSKMKDMRMDKSELGCLRAIV 376

  Fly   415 FFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFA 479
            .|:|:||||:.|..:::||.::...||.|...:..|..|||.::||.||.|:||..:.:|.:.|.
  Rat   377 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFF 441

  Fly   480 KIFGVAHIDSLLQEMLLGGELADNPLPLS 508
            |:.|...||:.|.|||      :.||.::
  Rat   442 KLIGDTPIDTFLMEML------ETPLQIT 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	46/74 (62%)
		NR_LBD_HNF4_like	264..494	CDD:132729	81/233 (35%)
Rxrg	XP_038947050.1	Nuc_recep-AF1	25..134	CDD:463363	22/94 (23%)
		NR_DBD_RXR	137..213	CDD:143514	45/108 (42%)
		NR_LBD_RXR_like	233..442	CDD:132741	77/227 (34%)