Protein Alignment Hnf4 and nhr-146

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001122810.1
• Gene: nhr-146 / 6418682
• WormBaseID: WBGene00045255
• Length: 365
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 84/392 - (21%)
• Similarity: 141/392 - (35%)
• Gaps: 91/392 - (23%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTC--RFARNCVVDKDKRNQCRYCRLRKCFK 232
            |.:|...:.|.|:|...|..|..||||:|.|...:.|  .....|.:.......|:.||..||..
 Worm     5 CPVCQALSNGFHFGVEVCSACSAFFRRTVFKKRNFRCWGEPVNCCEIVSTGSAFCKSCRFAKCLA 69

  Fly   233 AGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLS---- 293
            .|||||.||..|:              |.|...::||...::.:.::.|..:...|.|..|
 Worm    70 VGMKKETVQQGRE--------------GYGKREMALVPVISKFKANRQGLPILETIVETYSLLLN 120

  Fly   294 -----------------NKQFASINDVCESMKQQLLTLVEWAKQ-IPAFNELQLDDQVALLRAHA 340
                             :.:..:..:......::...:.:|... .|.|....:|.:..|.|...
 Worm   121 VRICVHEGPNGSNSPKRDPKPVNYKETIACFLKEFYLVGDWLSHCFPEFAAFPVDQKDLLHRNFY 185

  Fly   341 GEHLLL--GLSRRSMHLKDVLLLSN----NCVITR---HCPD---PLVSPNLDISRIGARIIDEL 393
            .:.::|  |....:....|:..|.:    :||...   :.||   |: :|.            |.
 Worm   186 LQFVVLEGGFFSCNHKRSDIRYLPSGDYIDCVNPETYYYDPDGKQPM-TPG------------EA 237

  Fly   394 VTV---------------MKDVGIDDTEFACIKALVFFDPNAKGLNEPHR--IKSLRHQILNN-L 440
            ||:               |.....|..||..:..|..||.:.:.::|...  .:.:|.:|..| |
 Worm   238 VTLFASSFQSYRRNVTHPMLRENADRFEFLALTGLALFDADLENISEETAAVCRKVRQKIQRNML 302

  Fly   441 EDYISDRQYESRG-RFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNP 504
            :.|||.:..|... |.|.::.|:|.|...|.:.:|.|:.:.:.....:|.         :..||.
 Worm   303 KYYISTKSPEDASVRLGNLISIIPSLHRATRRFLEDIELSHVMKAYAVDE---------KFYDNC 358

  Fly   505 LP 506
            ||
 Worm   359 LP 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/76 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	50/282 (18%)
nhr-146	NP_001122810.1	ZnF_C4	4..75	CDD:197701	23/69 (33%)
		Hormone_recep	132..338	CDD:278530	41/218 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910