Protein Alignment Hnf4 and hnf4g

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_021325864.1
• Gene: hnf4g / 557104
• ZFINID: ZDB-GENE-060929-100
• Length: 459
• Species: Danio rerio
• Alignment Length: 531
• Identity: 256/531 - (48%)
• Similarity: 313/531 - (58%)
• Gaps: 114/531 - (21%)

  Fly   130 GSNNNNSMFSPNN-----NLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDG 189
            |..|...::...|     |:|...:|.:|:               ||||||:|||||||||||||
Zfish    32 GFENAEVLYCGENMPTEPNISQGENGVSSN---------------CAICGDKATGKHYGASSCDG 81

  Fly   190 CKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSN 254
            ||||||||:||:|.|:|||.|.||||||||||||:|||.|||:||||||||||||||||.||...
Zfish    82 CKGFFRRSIRKSHVYSCRFNRQCVVDKDKRNQCRFCRLHKCFRAGMKKEAVQNERDRISSRRNIQ 146

  Fly   255 DDPD-PGNGLSVISLVKAENESRQS-KAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEW 317
            |..| |    .:.:|..||..|:|. .|.:.|.|   .|:|.|:.|:|:|||||||||||.||||
Zfish   147 DSHDLP----PITALAHAEALSQQQITAASPMGP---ADVSEKKSATISDVCESMKQQLLVLVEW 204

  Fly   318 AKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDI 382
            ||.||||.||.|||||:|||||||||||||:::|||..||:|||.|.|||.|:||:|      :|
Zfish   205 AKYIPAFGELPLDDQVSLLRAHAGEHLLLGVAKRSMSYKDLLLLGNGCVIHRNCPEP------EI 263

  Fly   383 SRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDR 447
            .|:..|::||||...:|:.|||.|:|.:||:|||||:||.|.:|.:||::|:|:..:|||||:||
Zfish   264 GRVSNRVLDELVLPFQDIQIDDNEYAALKAIVFFDPDAKSLRDPSKIKAMRYQVQMSLEDYINDR 328

  Fly   448 QYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELADNPLPLSPPNQ 512
            ||:|||||||:||:||.|||||||||||:||.|:||:|.||:|||||||||...:.|
Zfish   329 QYDSRGRFGELLLLLPTLQSITWQMIEQLQFIKLFGLAKIDNLLQEMLLGGLTTEQP-------- 385

  Fly   513 SNDYQSPTHTGNMEGGNQVNSSLDSLATSGGPGSHSLDLEVQHIQALIEANSADDSFRAYAASTA 577
                 ...|.|                               |.|..|...:
Zfish   386 -----HLHHNG-------------------------------HPQIPITGQT------------- 401

  Fly   578 AAAAAAVSSSSSAPASVAPASISPPLNSPKSQHQHQQHATHQQQQESSYLDMPVKHYNGSRSGPL 642
                 .|.||...||....||...|:.||          |..|.||       |...:||.:..|
Zfish   402 -----IVISSIPGPAHPQMASPETPIPSP----------TSVQNQE-------VFKPSGSPALLL 444

  Fly   643 PTQHSPQRMHP 653
            |.|..|.|..|
Zfish   445 PPQTMPNRPSP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	64/74 (86%)
		NR_LBD_HNF4_like	264..494	CDD:132729	140/230 (61%)
hnf4g	XP_021325864.1	NR_DBD_HNF4A	62..137	CDD:143518	64/74 (86%)
		NR_LBD_HNF4_like	154..375	CDD:132729	140/229 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	259	1.000	Domainoid score	I1950
eggNOG	1	0.900	-	-		E1_KOG4215
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1549
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003424
OrthoInspector	1	1.000	-	-		otm25745
orthoMCL	1	0.900	-	-		OOG6_105157
Panther	1	1.100	-	-	LDO	PTHR24083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2679
SonicParanoid	1	1.000	-	-		X1958
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.850