Protein Alignment Hnf4 and nhr-286

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001041174.1
• Gene: nhr-286 / 4363091
• WormBaseID: WBGene00044699
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 98/392 - (25%)
• Similarity: 151/392 - (38%)
• Gaps: 102/392 - (26%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKR-NQCRYCRLRKCFKA 233
            |.:|...:|..||||..|..|..||||.|......||....:|.:..::. .||:.||:.||.:.
 Worm     8 CLVCKAPSTEPHYGADVCRACAAFFRRRVFSRFPATCDQLGSCEITGEREVRQCKACRMEKCLQI 72

  Fly   234 GMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFA 298
            ||:...||::||     :..||.....:.:|..:||.| ..|:.|.....::.:...|.:|.:..
 Worm    73 GMRISNVQSKRD-----KHDNDKLKKKDEVSEKALVPA-CYSKVSILPNELQCSSTYDYNNMRLK 131

  Fly   299 SINDVCESMKQ------------------QLLTL--------VEWAKQ-IPAFNE-LQLDDQVAL 335
            |::.....|.|                  :.||:        |:|... .|.|:. |:.|.|..|
 Worm   132 SLHLNFTEMLQIRKVRFPKRRATKTLHHAEALTIFRKDVRLVVDWINHTFPEFSRVLEPDQQRIL 196

  Fly   336 LR-----------AHAGEHLLLGLSRRSMHLKDVLLLSN-NCVITRHCPDPLVSPNLD-ISRI-- 385
            .|           |:..  :||| ...:.||....::.. ....|||...| .|.:|| :|||
 Worm   197 FRNFYMKWTVFEPAYLA--VLLG-KPDTYHLPTGDIVDEVGVYYTRHLCTP-TSYSLDEVSRIFS 257

  Fly   386 --GARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEP-----HRIKSLRHQIL------ 437
              .|.....||..:.|..:...||..:.|:..||   .||:..     ...:::|.::.
 Worm   258 PYWADFRKTLVDPVIDAKLSIHEFLLLCAICLFD---IGLDYQSDDCIEFCQTIRQELFRELNAV 319

  Fly   438 ------NNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLL 496
                  :|.|||..        ||.:.:|:||.:|                  ..||.|.:|:.|
 Worm   320 CKQLCSSNSEDYCF--------RFSKNMLLLPSIQ------------------RGIDVLEEELQL 358

  Fly   497 GG 498
            ||
 Worm   359 GG 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/75 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	63/291 (22%)
nhr-286	NP_001041174.1	ZnF_C4	8..77	CDD:197701	25/68 (37%)
		Hormone_recep	147..355	CDD:278530	52/240 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910