Protein Alignment Hnf4 and nhr-138

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_501730.3
• Gene: nhr-138 / 3565904
• WormBaseID: WBGene00003728
• Length: 410
• Species: Caenorhabditis elegans
• Alignment Length: 400
• Identity: 96/400 - (24%)
• Similarity: 166/400 - (41%)
• Gaps: 89/400 - (22%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAG 234
            |.:|||....:|||..:|:||||||||||.:...|.|....:|.|.:..||:||.||..||...|
 Worm    15 CLVCGDDKASRHYGTVACNGCKGFFRRSVWEKRTYFCIANEDCEVLQQFRNRCRACRFNKCVMVG 79

  Fly   235 MKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNIN-----EDLSN 294
            |...|||:||:   .|.........|:.....|.::..|....|:..::..|:::     :.|.|
 Worm    80 MDARAVQSERE---IRPNETAKKPKGSLKGKRSSLQTSNSVTSSQPSSSSTPDVDHPPIVKHLFN 141

  Fly   295 KQ-----------------FASINDVCESMKQQL--------LTLVEWAK--------------- 319
            .|                 |.|:.:|..|::..|        .|.:||..
 Worm   142 IQRRVETTFCPEFDDLVARFGSMCNVRISLQSALENPEKVATRTKLEWGNTSRLADIHDLKVTWC 206

  Fly   320 --------QIPAFNELQ----LD-DQVALLRA----------HAGEHLLLGLSRRSMHLKDV--- 358
                    .:.:|.||:    || :|:..||.          |:.::.:.|::    ...|.
 Worm   207 RTFVWFHDYLSSFEELERLNYLDREQLFKLRFAPVSWNLYAWHSYQNNIDGVT----FTNDAWYP 267

  Fly   359 LLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGL 423
            |.......:.:.|.|       ..|:|...:|..||..||.:.:.:.||:|:.|:..|.|:.:..
 Worm   268 LDKEKQAFMDKPCND-------YYSKIADTMIHGLVYRMKGINMTEEEFSCMLAITLFRPDYRLS 325

  Fly   424 NEPHRIKSLRHQILNN-LEDYISDR---QYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGV 484
            ::.:::..|...:... |.:|:..|   :.::..|...::::|..:||:..|..:.:.|..||.:
 Worm   326 SDANKLLQLTGDVFTKALSEYVLSRETSELKAMERMATLMIMLTSVQSLARQEDDNVTFLAIFDM 390

  Fly   485 AHIDSLLQEM 494
            |.:..|..|:
 Worm   391 ADLVGLPYEV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	36/74 (49%)
		NR_LBD_HNF4_like	264..494	CDD:132729	56/304 (18%)
nhr-138	NP_501730.3	NR_DBD_HNF4A	15..90	CDD:143518	36/74 (49%)
		HOLI	205..374	CDD:214658	34/179 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910