Protein Alignment Hnf4 and nhr-140

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504768.1
• Gene: nhr-140 / 3565647
• WormBaseID: WBGene00016366
• Length: 346
• Species: Caenorhabditis elegans
• Alignment Length: 364
• Identity: 87/364 - (23%)
• Similarity: 141/364 - (38%)
• Gaps: 63/364 - (17%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVR-KNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKA 233
            |.:||.:::..|:|..||..|..||||.|. |..|..|    .|....|....|||||:.||.:.
 Worm     3 CGVCGAKSSESHFGGLSCRACAAFFRRYVNSKKPQIEC----TCSQKFDSSGPCRYCRMLKCVEV 63

  Fly   234 GMKKEAVQNERDR------ISCRRTSNDDPDPGNGLSVISLVKAENESRQ-SKAGAAME--PNIN 289
            ||.|..||..|.:      :.|..|:            |||:......|. ||....::  |:::
 Worm    64 GMAKCKVQATRQKNKEYVFLPCAITN------------ISLLSCNIIPRSCSKLTCTVKNWPDLD 116

  Fly   290 E---DLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQL---DDQVALLRAHAGEHLLLGL 348
            :   ||......::|....|.:.:..|.:.|......|:|:.|   ||:.|||.......:|:..
 Worm   117 KKRRDLYGGSMYNLNFTQFSNRVRQDTTIFWDLAESIFSEIGLLNSDDKDALLCNFFPRWMLMEA 181

  Fly   349 S-----RRSMHLK----DVLLLSNNCVITRHCPDPLVSPNLDISRI-------GARIIDELVTVM 397
            :     ....|.|    |.|   :|.::..:.........||..:|       ..|...|:...:
 Worm   182 AIEYCKNYEHHWKMIETDGL---DNMLLVFYGSSMPKEKRLDDDKIIQIFRPYWTRFYIEIAEPI 243

  Fly   398 KDVGIDDTEFACIKALVFFDPNAKGLNE--PHRIKSLRHQILNNLEDYISDRQYESRGRFGEILL 460
            .....|..||..:..|:.||.....::|  ....::|:..||..|:.|..|... |..||.:::.
 Worm   244 HQEKCDKVEFMALFLLILFDDAYLNISEEAAKLCRNLQKVILRELKGYQMDNNC-SEMRFMDVIS 307

  Fly   461 ILPVLQSITWQMIEQIQFAKIFGVA---------HIDSL 490
            .|.:.:....::.|:|....:..::         ||..|
 Worm   308 KLSLFERGEKRLQEEIVICDVIDISLDEDFKTIMHIKKL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/75 (40%)
		NR_LBD_HNF4_like	264..494	CDD:132729	54/263 (21%)
nhr-140	NP_504768.1	ZnF_C4	3..65	CDD:197701	25/65 (38%)
		HOLI	154..314	CDD:214658	36/163 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910