Protein Alignment Hnf4 and nhr-168

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001256501.1
• Gene: nhr-168 / 353455
• WormBaseID: WBGene00008221
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 82/393 - (20%)
• Similarity: 154/393 - (39%)
• Gaps: 92/393 - (23%)

  Fly   153 SSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKD 217
            :::.:...:|:.|.|:.|:|||..|.|.||...||:|||.||||.......:.|:...:| .:..
 Worm    33 TARSESPARQRHQRPSECSICGKTANGYHYDVPSCNGCKTFFRRLCVSEKSFICKAGGDC-FNLT 96

  Fly   218 KRN---QCRYCRLRKCFKAGM--------KKEAVQNERDRISCR--RTSNDDPDPGNGLSVISLV 269
            ||.   :||.||..||...||        :|||......::..|  :::..|||..:|..:...:
 Worm    97 KRKVPLKCRACRYEKCISEGMNPNAMLLDEKEATAENFKKLKKRVNQSNPKDPDDDSGEDIEHQI 161

  Fly   270 KAEN--------ESRQSKAGAAME---------------------PNINEDLSNKQFASINDVCE 305
            :.:.        |::..|....:.                     |.:...|..:...|:.|...
 Worm   162 EKKQVIKDVACIENKMQKLVDMLNYLERKVTKFRMSAYNPHWSTLPGLEAFLLLENKISLADRSG 226

  Fly   306 SM-----KQQ-----------------------------LLTLVEWAKQIPAFNELQLDDQVALL 336
            .|     |.|                             |:..:|:||....|::|...|::.|:
 Worm   227 PMPGWPLKTQSSPPKIPEFGKKPTGPAYSPDQKCWILYDLMVSIEYAKTFMFFHQLDSRDRLVLM 291

  Fly   337 RAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVG 401
            |       .:.|:..::|:....:......|..  ||..::| :....:.|..:..:..::: ..
 Worm   292 R-------YVALALMNLHISYFTVAKKYDTIIH--PDGKLAP-MKKGMVYAETVMSIAPLIR-CE 345

  Fly   402 IDDTEFACIKALVFFDPNAKGLNEPHRIKSL---RHQILNNLEDYISDRQYESRGRFGEILLILP 463
            |.:|||..:||:...:|....|:: |..:.|   |.|..:.|.|:....:.:...:|.|::.::.
 Worm   346 IQETEFVLLKAICLCNPAVPDLSQ-HAQEILGREREQYADALFDHCLRNRKDGPSQFAELIGMVD 409

  Fly   464 VLQ 466
            :|:
 Worm   410 LLE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	32/85 (38%)
		NR_LBD_HNF4_like	264..494	CDD:132729	42/269 (16%)
nhr-168	NP_001256501.1	ZnF_C4	50..120	CDD:197701	29/70 (41%)
		HOLI	264..414	CDD:214658	33/161 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010