Protein Alignment Hnf4 and nhr-78

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_500530.2
• Gene: nhr-78 / 191727
• WormBaseID: WBGene00003668
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 83/395 - (21%)
• Similarity: 156/395 - (39%)
• Gaps: 72/395 - (18%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTC-RFARNCVVDKDKRNQCRYCRLRKCFKA 233
            ||||...|...|:||.||..|..||||:|..:..|.| ....:|.|:.::|..|:.||.:||...
 Worm     3 CAICDSVALSLHFGAPSCKACAAFFRRTVALDITYDCITGTLDCEVNFERRMACKRCRYQKCIDN 67

  Fly   234 GMKKEAVQNERDRISCRRTSNDDPDPGNGLS---------------------VISLVKAENESRQ 277
            .|::..||:::.|... .|:|...:|....|                     ::|.::.:...:.
 Worm    68 NMQRYLVQSKKGRPDA-STANGIENPTTSASPSIPSPFSPPCPSSHNSAPSGLLSPMETDEIQKL 131

  Fly   278 SKAGAAMEPNINED----LSNKQFASI-NDVCES------------------MKQQLLTLVEWAK 319
            ::....|:.|:|:.    .::.:...| :.||:.                  .||:.:.|..:|.
 Worm   132 NEHFFKMDSNLNKSRRMAFTDSRLLDIFSGVCKMPFEKHQLQPFDFRSYRGYQKQEYVMLFNYAN 196

  Fly   320 QIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHL--KDVLLLSNNCVITRHCPDPLVSP---- 378
            .:|.|.||....|..|.|...|...::..|..::.:  :..||::.:....:..|.||:..
 Worm   197 TLPGFQELSNASQNFLFRIACGVDYVISSSYYTLCIGTESNLLINQDGTYIQMMPLPLMGDEPGT 261

  Fly   379 --------------NLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE--PH 427
                          |:...|:.:.:  |.:.:.|.:.:...|.|.:|||..:......|.|  ..
 Worm   262 ELMFTRKEELEKYRNIIKPRVNSWL--EFIPLFKSLELSFEENAILKALCCWQTAHFKLEECDKE 324

  Fly   428 RIKSLRHQILNNLEDYISDRQYESRG--RFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSL 490
            .::..:..::..|..:..|...|..|  |.|.|:|....:.:...:::..:.....|.:...|.|
 Worm   325 NVRKQKSLLVQCLLKFCIDTYGEEEGPARAGNIILFSSSISAEVMELVNSLIIMSFFEIMECDPL 389

  Fly   491 LQEML 495
            :.|:|
 Worm   390 INEIL 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	29/75 (39%)
		NR_LBD_HNF4_like	264..494	CDD:132729	48/297 (16%)
nhr-78	NP_500530.2	ZnF_C4	2..69	CDD:197701	26/65 (40%)
		HOLI	184..359	CDD:214658	36/176 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910