Protein Alignment Hnf4 and nhr-38

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_501728.2
• Gene: nhr-38 / 191720
• WormBaseID: WBGene00003629
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 366
• Identity: 100/366 - (27%)
• Similarity: 141/366 - (38%)
• Gaps: 90/366 - (24%)

  Fly   152 NSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNC--VV 214
            |||..|         ..:|:||.|:|.|.|:||.||..|..||||||.....|:|. .|.|  |.
 Worm    24 NSSAPQ---------EMICSICSDKAEGYHFGAISCAACGAFFRRSVSDQKVYSCS-NRQCSIVH 78

  Fly   215 DKDKR-NQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENES--- 275
            |..|| ..||:||..||..:||..:.|:       .:|||:...      :|.||.:..|:|
 Worm    79 DPTKRGGSCRFCRFLKCVSSGMMPQDVK-------AKRTSSSQQ------NVTSLYRNMNQSSIL 130

  Fly   276 --------RQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQ 332
                    |:|.  ||..|..  ||.::.....|     :|..|....|..::|...:.| :...
 Worm   131 LIDQIIAFRRSI--AAERPIF--DLISRSTTRTN-----LKISLHQEYEIMRRISTGSPL-IMQV 185

  Fly   333 VALLRAHAGEHLLLGLSRRSMHLKDVLLL---SNNCVITRHCP----DPLVSPNLDISRIGARII 390
            :....||.|.   |..:..|..|.|:.||   ...||:|....    |.|..||
 Worm   186 IEHFYAHFGS---LDNNFMSDPLGDIFLLVFVFEACVLTATKGGIQLDRLFLPN----------- 236

  Fly   391 DELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYIS--DRQYESRG 453
                  |..:.:.:..|     |.|.:........|:|      .|||:....:.  .|.::| .
 Worm   237 ------MVHIDLSEQPF-----LEFMECEQHVNLNPYR------NILNSFSFLVQLVSRSFQS-C 283

  Fly   454 RFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEM 494
            .|.|.||.:...:.||..:  .|.|...|...:.||||.::
 Worm   284 NFDEPLLSILFYKCITEAV--PINFRHCFADVNRDSLLTDL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	35/77 (45%)
		NR_LBD_HNF4_like	264..494	CDD:132729	58/249 (23%)
nhr-38	NP_501728.2	ZnF_C4	32..102	CDD:197701	34/70 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910