Protein Alignment Hnf4 and nhr-17

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_510115.1
• Gene: nhr-17 / 191719
• WormBaseID: WBGene00003616
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 354
• Identity: 92/354 - (25%)
• Similarity: 169/354 - (47%)
• Gaps: 40/354 - (11%)

  Fly   151 TNSSQQQLQQQQQQQSP-TVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVV 214
            ||.|:|:.::..::..| .:|::|||.|:|.||..::|:|||.||||.|.:|..|:|:...:|::
 Worm    11 TNYSRQKAKEMAKKFIPGELCSVCGDVASGIHYSVAACNGCKTFFRRVVLENRTYSCKNNGDCII 75

  Fly   215 DKDKRNQCRYCRLRKCFKAGMKKEAVQNERDR----ISCRRTSNDDPDPGNGLSVISLVKAENES 275
            ||..|..||:||.:||..|||.:..:..||.|    ::....|.:..:..:.|..:.|.|.....
 Worm    76 DKSMRCSCRHCRYKKCIIAGMDRGELSMERRRKRKKLNGLEGSEESWETEDALINLLLYKETLYQ 140

  Fly   276 RQSKAGAAM-EPNINEDLSNKQFASINDVCESMKQQ----------------LLTLVEWAKQIPA 323
            :...:.|.| ..::.|.|...|.| .||...:..::                |..||||||....
 Worm   141 KLLLSSAMMIHTSLREALDMTQIA-FNDENHTYDERMDPKYPTNFSYWRAKILTVLVEWAKSFEV 204

  Fly   324 FNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKD-----VLLLSNNC----VITRHCPDPLVSPN 379
            |:.|..:||..|....|..:|:|.   .:.|..:     ::.....|    |......|.:.:..
 Worm   205 FSHLIPEDQKRLFIHTAFSNLVLA---EAFHTPEKYNDRIVFPDGLCGFRNVAQSVSTDGVSNKT 266

  Fly   380 LDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE--PHRIKSLRHQILNNLED 442
            ..::.....:|::::..::.:.:...|:..::|::||||:...|.:  ...|.:.|.::|::|:.
 Worm   267 FGLTPTVVAVINDVLVPIRRMRLTKVEYVLLQAIIFFDPDCLSLTKHGSQLIAAKRKRLLDSLQK 331

  Fly   443 YISDR---QYESRGRFGEILLILPVLQSI 468
            ::..:   ..|:..||.||||.:..:|.:
 Worm   332 WLHQQTKDSIEASTRFAEILLRICNVQKV 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	34/74 (46%)
		NR_LBD_HNF4_like	264..494	CDD:132729	49/236 (21%)
nhr-17	NP_510115.1	NR_DBD_HNF4A	31..105	CDD:143518	33/73 (45%)
		NR_LBD	182..360	CDD:132726	39/180 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010