Protein Alignment Hnf4 and nhr-242

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001343692.1
• Gene: nhr-242 / 190547
• WormBaseID: WBGene00022097
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 348
• Identity: 89/348 - (25%)
• Similarity: 149/348 - (42%)
• Gaps: 63/348 - (18%)

  Fly   144 LSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRF 208
            :|..||.|:||      ....|:..:||:||.:|:...|||.||.||..||||......::.|..
 Worm     1 MSSLGSTTSSS------TPSSQTSELCAVCGGKASSSRYGALSCIGCLVFFRRMTCGEKKWYCLR 59

  Fly   209 ARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAEN 273
            .|||.::...||.||.|||:||...||...|:| .||.|..|:
 Worm    60 NRNCEINIATRNTCRACRLQKCLNVGMNPNAIQ-RRDEIGPRK---------------------- 101

  Fly   274 ESRQSKAGAAMEPNINEDLSNKQF--ASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALL 336
                        |.::: .|.||:  |:.::....:.......:|||.|:.:|:.|...|:..:|
 Worm   102 ------------PKVSK-FSQKQYNAATSSECAMCLHIGFQNALEWANQLESFSMLSHVDKQNIL 153

  Fly   337 RAHAGEHLLLGLSRRSMHLKD--VLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKD 399
            ..:.....|:....::....|  ..||.|..|:  ||.....|.:.|:..   ::|..:...:|.
 Worm   154 SEYGIAFTLIDQGYKTARDADEQCWLLQNGSVL--HCEQLFNSSDADLVN---QLIANISQPLKR 213

  Fly   400 VGIDDTEFACIKALVFFDPNAKG---LNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLI 461
            :.:|:.|...:|:|:....:..|   ||.    :..|.:.|..:..:.:|.:     |||||:|:
 Worm   214 LELDEYECGLLKSLLLLSSSFPGEVQLNS----QQSRAKCLTEMLQHRNDPE-----RFGEIILL 269

  Fly   462 LPVLQSITWQMIEQIQFAKIFGV 484
            :..::|.......|.:.:.:|.|
 Worm   270 IGSIRSSVKLFYNQTKRSDLFNV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	33/74 (45%)
		NR_LBD_HNF4_like	264..494	CDD:132729	45/228 (20%)
nhr-242	NP_001343692.1	NR_DBD_HNF4A	21..96	CDD:143518	34/75 (45%)
		Hormone_recep	105..289	CDD:306586	42/198 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910