Protein Alignment Hnf4 and nhr-135

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504798.2
• Gene: nhr-135 / 189066
• WormBaseID: WBGene00003725
• Length: 362
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 85/381 - (22%)
• Similarity: 140/381 - (36%)
• Gaps: 100/381 - (26%)

  Fly   166 SPTVCAICGDRATGKHYGASS--CDGCKGFFRRSV-RKNHQYTCRFARNCVVDKDKRNQCRYCRL 227
            ||..|.:|...|...|:|:.|  |..|..||||.| .......||..::|.:.......||:||:
 Worm     2 SPHPCFVCNSPANECHFGSRSQICRACSAFFRRYVLSPKSAIKCRKDKSCRIHYKDPKICRFCRM 66

  Fly   228 RKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDL 292
            .:|..||||..|||..|::.|        .|.|:         :|..|..|.:     |..:|..
 Worm    67 ERCVLAGMKTTAVQPPREKYS--------EDRGD---------SETSSCYSSS-----PYTHEVQ 109

  Fly   293 SNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHL-- 355
            |          |.....:|..|....|.:.:..:|:..:|......:..|  |:.:.::.|.|
 Worm   110 S----------CSRDIPRLHRLSVHFKNLESVRKLEFQNQEPPKSRNMVE--LIEILKKDMRLVS 162

  Fly   356 ------------------KDVLLLSNNCVITRHCPDP-----------LVSPNLD---------I 382
                              |.|.|   |..|.....:|           ::.||.|         .
 Worm   163 TFIDGAYPEIGKLGHLEKKQVFL---NFFIKYMLVEPPFLSISAGRKEMMLPNGDHYDEDLGAFY 224

  Fly   383 SRIGARIIDELV------------TVMKDVGI---DDTEFACIKALVFFDPNAKGLNEP--HRIK 430
            |.|..: .:|.|            ||:.||..   |..||..:..|:.:|....||::.  ...:
 Worm   225 STINVK-KEEAVHLFKPYWDEYKRTVIDDVSFLKPDVYEFLTVSGLILWDTGLDGLSDQSIEICR 288

  Fly   431 SLRHQILNNLEDYISD--RQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGV 484
            ::|.:::..:..|..:  :..:...|.|:|::||..:|....:..|::|....|.:
 Worm   289 AMREKLVGEIHFYYKNVKKLDDPCLRLGQIMMILSSVQKSFGKYQEELQMCGFFEI 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/77 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	51/280 (18%)
nhr-135	NP_504798.2	ZnF_C4	5..75	CDD:197701	23/69 (33%)
		Hormone_recep	136..335	CDD:278530	37/204 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910