Protein Alignment Hnf4 and nhr-223

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001359598.1
• Gene: nhr-223 / 188934
• WormBaseID: WBGene00012050
• Length: 281
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 68/317 - (21%)
• Similarity: 124/317 - (39%)
• Gaps: 75/317 - (23%)

  Fly   193 FFRR-SVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDD 256
            |||| ::||.....|.....|..|......|::||.:||.:.||..:|:        .::||.:
 Worm     2 FFRRQAIRKCALRPCSGGEACYRDTPLILGCQFCRFQKCIEVGMNIKAL--------LQKTSLE- 57

  Fly   257 PDPGNGLSVISLVKAENESR--------QSKAGAAMEPNINEDLSNK---QFASINDVCESMKQQ 310
                   |:|:.:...:..|        ..:||..:. |:.|:...:   :...:|..|......
 Worm    58 -------SLINFISDVDFERCITFLNFYPKQAGYTIW-NVVENFPIEYIHRSQPLNYRCWLFLTA 114

  Fly   311 LLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITR------ 369
            :.| :::.|:.|........||..:||                  |..:.:::.|...|
 Worm   115 VST-IDFMKKFPFVFLSNSHDQTIILR------------------KKFVKVASFCEAFRVYLFRD 160

  Fly   370 ---HCPD--PLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRI 429
               ..||  .::...|| |.:|.||...||....::.|.:.||..:..|:|.:|..:.|::
 Worm   161 KQLAFPDGSSILIEGLD-SELGDRIKYRLVVTFFELHITNEEFLLLLVLLFSNPAIESLSQ---- 220

  Fly   430 KSLRHQILNNLEDYISDR-------QYESRG--RFGEILLILPVLQSITWQMIEQIQ 477
              ...::|:..::|.|..       .|...|  ||.|:|.:..||.:..:|:.|.::
 Worm   221 --TGSRLLSAYQNYYSSSLLEYCMLTYLKNGPTRFAELLDVFQVLTNPEFQLDEIVK 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	17/52 (33%)
		NR_LBD_HNF4_like	264..494	CDD:132729	49/245 (20%)
nhr-223	NP_001359598.1	NR_DBD_like	<2..49	CDD:383039	16/46 (35%)
		HOLI	110..265	CDD:214658	38/180 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910