Protein Alignment Hnf4 and nhr-127

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001370055.1
• Gene: nhr-127 / 188480
• WormBaseID: WBGene00003717
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 85/359 - (23%)
• Similarity: 139/359 - (38%)
• Gaps: 95/359 - (26%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFA-RNCVVDKDKRNQCRYCRLRKCFKA 233
            |.:|.:::.|.|:...||..|..||||||....:|.|:.. :.|.:....|:.|||||..||.||
 Worm    13 CEVCKNQSNGYHFEVLSCGACASFFRRSVVSKIKYQCKDGKKRCQIRYLDRHFCRYCRFSKCVKA 77

  Fly   234 GMKKEAVQNERDRISCRRTSNDDPD--PGNGL--------SVISLVKAENESRQSKAGAAMEPNI 288
            |||.|.:|..|| :....|..|..:  |.:.|        .:..|.|..|....|:..:.:| .:
 Worm    78 GMKAEKIQKNRD-LDSSPTPTDQNNCIPSDVLHDDGILIKDIRGLFKQFNPHNASEGCSKLE-KL 140

  Fly   289 NEDLSNKQFASIND------VCESMKQQLLTLVE---------WAKQIPAFNELQLDDQVALLRA 338
            .|.|   ||...|.      :.:.|..:.|..|:         |......|.:|:.:::|.:|
 Worm   141 TEGL---QFIRRNQERECIKIIDEMDSESLKDVQFKVIGSCATWLLFSSFFQKLEENEKVVIL-- 200

  Fly   339 HAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGID 403
                       .|..|...||              ..:|.:|:|  .|.::|||.:..:.|
 Worm   201 -----------ERLWHGWTVL--------------EFLSRSLEI--FGNKVIDEKIVFISD---- 234

  Fly   404 DTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSI 468
               ...|:.:..|:.:.|..: |.:.:|::.::           :......|.|:     .|..|
 Worm   235 ---NTAIRLITAFENSLKTAS-PKKSESIKKKL-----------ELSFSVIFDEL-----ALHFI 279

  Fly   469 TWQ----MIEQIQFAKIFGVAHIDSLLQEMLLGG 498
            .|:    .|..:|:..::.||       |.||.|
 Worm   280 NWKPTEIEISYMQWQIVWSVA-------EQLLSG 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	31/75 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	44/248 (18%)
nhr-127	NP_001370055.1	ZnF_C4	12..82	CDD:197701	29/68 (43%)
		Hormone_recep	156..352	CDD:395054	38/211 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910