Protein Alignment Hnf4 and nhr-218

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_507103.2
• Gene: nhr-218 / 188479
• WormBaseID: WBGene00011750
• Length: 391
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 86/412 - (20%)
• Similarity: 153/412 - (37%)
• Gaps: 108/412 - (26%)

  Fly   152 NSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARN-CVVD 215
            :|.|..|:....|  |..|.||..::.|.::...:|..|..|||||:....:|.|:..:| |.:|
 Worm     4 SSFQHHLEPMLTQ--PIPCQICTYQSHGVNFNVMTCRACAAFFRRSLVCGMRYHCKTRKNDCRID 66

  Fly   216 KDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKA 280
            ..:|:.||.||.:||.:.|||.|.:|..||.||                            .:..
 Worm    67 STERHFCRLCRFQKCLQMGMKAEKIQQNRDPIS----------------------------STFP 103

  Fly   281 GAAMEPNINE--DLSNKQFASINDVCESMKQQLLTLVEWAKQIPA-FNE---LQLDDQVALLRAH 339
            |.:.||.::|  |..|::....:......| .||..|.:...|.. :::   ..|::...|:..|
 Worm   104 GTSTEPELSEIVDPENEKSYIFHGTLYGFK-SLLAEVRYIFSISRNYSDSPLTDLENGFKLITRH 167

  Fly   340 AGEHLLLGLSRRSMHLKDVLLLSN----------NCVI----------------------TRHCP 372
            .        .||.:.::|.:...|          ||..                      |.|..
 Worm   168 Q--------KRRYIDIEDRINFQNLTDFRLGHIKNCATWLTHSSFFQSLTETENLLILKSTWHVW 224

  Fly   373 DPLVSPNLDISRIGARIIDE-LVTVMKDVGIDDTEFACIKALVFFDPNAKGLN--EPHRIKSLRH 434
            ..|...::.:...|.::.:| :|.:.:.:.:|     .:|...:.   .|.||  |..:::...:
 Worm   225 SWLELLSVSVEIFGNQVCEEKIVFLSEKIAVD-----IVKVFRYI---LKPLNKQEKRKVEKELN 281

  Fly   435 QILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGE 499
            .|.:.|.|.::.:....:....||..   :|..:.|.:.|::             |.::.|..||
 Worm   282 PIFHILFDDVARKLQNLKPSSLEINY---MLWQLVWFVAEKV-------------LNEDNLRHGE 330

  Fly   500 LADNPLPLSPPNQSNDYQSPTH 521
            ...|.|   ..:..|.|::..|
 Worm   331 QYTNQL---ASDLHNHYKNDLH 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/75 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	41/270 (15%)
nhr-218	NP_507103.2	ZnF_C4	19..89	CDD:197701	26/69 (38%)
		Hormone_recep	177..376	CDD:278530	33/200 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910