Protein Alignment Hnf4 and nhr-130

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503216.1
• Gene: nhr-130 / 187965
• WormBaseID: WBGene00003720
• Length: 440
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 98/412 - (23%)
• Similarity: 154/412 - (37%)
• Gaps: 100/412 - (24%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRS-VRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKA 233
            |.:|...|.|.|:||.||..|..||||: ......|.|:...||.:.::.|.:|:.|||.:|.:.
 Worm    37 CQVCALPAHGNHFGAISCRACAAFFRRACTGTKTTYKCKKQNNCDIWENGRYKCKKCRLDRCNEV 101

  Fly   234 GMKKEAVQNERDRISC----------RRTSNDDPDP-------GNGLSVISL---VKAENESR-- 276
            ||.....|.:||.||.          |||......|       |....:|.|   :.:.:|..
 Worm   102 GMDPGRFQFDRDLISATEKYPNSKNFRRTFGMSRLPETIEHFLGRPHFIIFLERHIYSHSEKNFV 166

  Fly   277 -----QSKAGAAME-----PNINEDLSNKQFASINDVCE----SMKQQLLT-------LVEW--- 317
                 .:||...:|     |.|..:...|....:|.|.:    |...||:|       |..|
 Worm   167 DLQHLIAKASKLLELGSEKPLIARNNLEKLALGLNLVRDQPAGSHDVQLVTKLGKDEALTFWETD 231

  Fly   318 ----AKQIPAFNELQL---DDQVALLRA--HAGEHL----LLGLSRRS--MHLKDVLLLSNN--- 364
                ||.:..|::.||   :.|:.||::  |....|    |...|||.  ...|.::|..|:
 Worm   232 FLTVAKWLTYFDDFQLLPHNQQILLLKSVWHVWNRLEKLALTATSRRQNVCEQKQLMLTYNSVCN 296

  Fly   365 -------------------CVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACI 410
                               |.......|.:::..||           .:|.::...|:.|...|
 Worm   297 PKTIELDYSWFTKYPKEQLCFFFDEMEDYMLTSALD-----------PLTSLEPTDIELTYMLC- 349

  Fly   411 KALVFFDPNAKGLNEPHRI-KSLRHQILNNLEDYISDRQYESR--GRFGEILLILPVLQSITWQM 472
             .|.|.....:...|...: :..:..:.:||.||..:.....|  ||..::|.|..::|...|:.
 Worm   350 -QLCFHYAGKRYGGEILEVTEKFQENLADNLHDYYVNELNMPRYCGRLNQMLKINNLIQQDIWEK 413

  Fly   473 IEQIQFAKIFGVAHIDSLLQEM 494
            ..:.:.||:|.:..|:....||
 Worm   414 RAKHELAKVFDIFCIEFSHPEM 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/75 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	60/298 (20%)
nhr-130	NP_503216.1	ZnF_C4	36..105	CDD:197701	26/67 (39%)
		Hormone_recep	210..416	CDD:278530	45/218 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910