Protein Alignment Hnf4 and nhr-125

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504194.2
• Gene: nhr-125 / 187520
• WormBaseID: WBGene00003715
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 86/376 - (22%)
• Similarity: 136/376 - (36%)
• Gaps: 80/376 - (21%)

  Fly   166 SPTVCAICGDRATGKHYGASSCDGCKGFFRRSV-RKNHQYTCRFARNCVVDKDKRNQCRYCRLRK 229
            ||..|.||..:|.|.|:|..:|..|..||||:. .|..|..|: ...|     .||.|:.|||:|
 Worm     9 SPFSCRICNQKAHGNHFGVLTCRACASFFRRAAFSKWSQLKCQ-KGGC-----SRNFCKRCRLKK 67

  Fly   230 CFKAGMKKEAVQNERDRISCRRTSNDD-PDPGNGLSVIS----LVKAENESRQSK---------- 279
            |.:.||.....|..||  |.|.|.... |.|.:..|.:.    .:..:.|:..:|
 Worm    68 CREMGMDTTKFQYNRD--SFRATGQFQLPPPRSLASFVGRPELFLFCDTEAPNAKMLIDVRYLLE 130

  Fly   280 --------------AGAAMEPNINE----------DLSNKQFASINDVCESMKQQLLTLVEWAKQ 320
                          :|.....|:.|          ::|:.::||.:.:....:....|:..|...
 Worm   131 EAGRIINQGYETPASGKNQLENLTEGFKYIKVDMNNISSSKYASKDAIISMWEYYFFTVTRWLMY 195

  Fly   321 IPAFNELQLDDQVALLRA--HAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPD---------- 373
            ...|.:|....|:.|:::  :....|...::....|..:...|..|.||.....|
 Worm   196 FEGFQKLNSHTQITLIQSVWNVWSRLHKYVATVDYHKANPDTLPTNVVIHNTLVDIENVEFDSTW 260

  Fly   374 ----PLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRH 434
                |:......:|....|..|.|.|:.| :...:.|...:.|.:.|:  ..|......|..:..
 Worm   261 LSDYPVEHVRRYLSVQHCREFDILGTLRK-LNPSELEITYLFAQICFE--HAGKRNQGDIMKVTE 322

  Fly   435 QIL----NNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKI 481
            |.|    |:|.||..:....|| .|..:..:|.:.|:        |||:.|
 Worm   323 QFLDSLANDLHDYYVNEMNNSR-YFLRLTQLLKINQA--------IQFSDI 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/75 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	49/276 (18%)
nhr-125	NP_504194.2	ZnF_C4	13..74	CDD:197701	26/66 (39%)
		Hormone_recep	165..360	CDD:278530	39/206 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000