Protein Alignment Hnf4 and nhr-189

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504065.2
• Gene: nhr-189 / 185913
• WormBaseID: WBGene00018545
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 357
• Identity: 82/357 - (22%)
• Similarity: 146/357 - (40%)
• Gaps: 76/357 - (21%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKR-NQCRYCRLRKCFKA 233
            |.|||..|:..:||..||:.||.||||.|.:...|.|:....|:.:..:. .||:.||..||.:.
 Worm    22 CTICGRDASCHNYGVLSCNACKMFFRRVVIEQLTYHCKKWNMCLENSGQPILQCKACRFEKCLQL 86

  Fly   234 GM---KKEAVQ---------------------NERDRIS-CRRTSNDDPDPGNGLSVISLVKAEN 273
            ||   :.|.:|                     |...|.. |...:::||      ::..:|:...
 Worm    87 GMTLGQLEKIQLPDLIHPDFKSDSLIKNVMFLNSTKRFKLCNFYTSEDP------TLEDMVQRTK 145

  Fly   274 ESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRA 338
            .||..:.            :.||..|:.   |...|.:...||....:...|.::.||::.|||.
 Worm   146 RSRMKRK------------TGKQVISVE---EWSFQAIYIAVEMFLSLDFMNSIENDDKIVLLRN 195

  Fly   339 HAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPD------PLVSPNLDISRIGARIIDELVTVM 397
            .:.:.:.|..:.||::.|      .:.|||   ||      .|:.....|..:.: |...||..:
 Worm   196 FSSKSMQLDSAMRSLNAK------VDRVIT---PDGNEVYSDLLLAMFSIDFLNS-IRSSLVVRV 250

  Fly   398 KDVGIDDTEFACIKALVFFDPNAKGLNE-PHRIKSLRHQILNN--LEDYISDRQYESRGRFGEIL 459
            :::.:.:.|.|.:..|:|.:|....|:| ..|:.:.|.:..::  |:..:...|.....||.::|
 Worm   251 EELKVTEQEHALLNFLLFCNPAIHPLSERTRRLLATRQKSYSSALLQYCLLTYQQSGPSRFADLL 315

  Fly   460 LILPV----------LQSITWQMIEQIQFAKI 481
            .:..|          |.::....:.|::..|:
 Worm   316 SLSHVINKTSEDANSLTTLCQMYMPQVKLKKL 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/99 (30%)
		NR_LBD_HNF4_like	264..494	CDD:132729	48/237 (20%)
nhr-189	NP_504065.2	ZnF_C4	21..89	CDD:197701	26/66 (39%)
		HOLI	164..324	CDD:214658	38/169 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910