Protein Alignment Hnf4 and nhr-188

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504064.1
• Gene: nhr-188 / 185912
• WormBaseID: WBGene00018544
• Length: 353
• Species: Caenorhabditis elegans
• Alignment Length: 378
• Identity: 86/378 - (22%)
• Similarity: 159/378 - (42%)
• Gaps: 88/378 - (23%)

  Fly   165 QSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDK-RNQCRYCRLR 228
            :|...|.|||..|:..:||..:|:.||.||||.|.:...|.||..:.|:.:.|: :.:|:.||..
 Worm    12 RSTLKCLICGRNASCHNYGVLTCNACKMFFRRVVIEQITYQCRNWKKCLENADQFKPRCKACRFE 76

  Fly   229 KCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLS 293
            ||.:.|||...:..|:   ..:......||.... ::|..|...|.:::.|            |.
 Worm    77 KCVRLGMKLGPIAMEK---LYKTKPMSHPDFATN-ALIQEVLYLNYTKRYK------------LC 125

  Fly   294 NKQFASINDVCESMKQ-------------QLLTLVEWAKQ-----------IPAFNELQLDDQVA 334
            | .:.|.|...|.|.|             |.:::.||:.|           :...|.::.|::|.
 Worm   126 N-FYTSENPTLEEMVQTTFWSGMKRKTEKQEISVAEWSFQATYIAVETFLSLEFMNLIENDEKVV 189

  Fly   335 LLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSP-------NLDISRIGARIIDE 392
            |||..:.:.::|..:.|:::.|               .|.:.:|       ::.:|...|..::.
 Worm   190 LLRNFSSKSIVLDSAMRALNAK---------------VDRVTTPDGEDIYSDIILSMFSAGFLNS 239

  Fly   393 ----LVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE-PHRIKSLRHQILNN--LEDYISDRQYE 450
                ||:.:.::.:.:.|.|.:..|:|.:|....|:| ..|:.:.|.:..::  |:..:...|..
 Worm   240 IQCGLVSRVAELKVTELEHAMLSVLLFCNPAIHPLSERTRRLLATRQKSYSSTLLQYCLLSYQQS 304

  Fly   451 SRGRFGEILLILPVL-------QSITWQMIEQIQFAKIFGVAHIDSLLQEMLL 496
            ...||.::|.|..|:       .|:|  .:.|:.|.|        |.|:.:|:
 Worm   305 GPSRFADLLSISHVINKTSEDANSLT--TLCQLYFPK--------SKLKHLLI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	29/75 (39%)
		NR_LBD_HNF4_like	264..494	CDD:132729	53/274 (19%)
nhr-188	NP_504064.1	ZnF_C4	16..84	CDD:197701	26/67 (39%)
		HOLI	162..322	CDD:214658	32/174 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910