Protein Alignment Hnf4 and nhr-186

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504063.1
• Gene: nhr-186 / 185909
• WormBaseID: WBGene00018541
• Length: 370
• Species: Caenorhabditis elegans
• Alignment Length: 404
• Identity: 91/404 - (22%)
• Similarity: 160/404 - (39%)
• Gaps: 95/404 - (23%)

  Fly   144 LSGSGSGTNSSQQQLQQQQQQQSPTV-----CAICGDRATGKHYGASSCDGCKGFFRRSVRKNH- 202
            :|.:.|..:.....|....:.::..|     ||:||..|...:||..||:.||.|||| |..:|
 Worm     1 MSANPSPDSCGSDYLPTDMEPETSAVSVSEKCAVCGKPAFCYNYGVLSCNACKMFFRR-VEVDHI 64

  Fly   203 QYTCRFARNC-----VVDKDK-RNQCRYCRLRKCFKAGM------------------KKEAVQNE 243
            .|.|::...|     .||.:. ..:||.||.|:|...||                  |...:..|
 Worm    65 TYNCKYWNTCYDGQEYVDANNVSTRCRACRYRRCIDLGMRYIAPGKPDLELVNQVDGKLNTLLQE 129

  Fly   244 RDRISCRRT-------SNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASIN 301
            ...:..||:       ::::|      ::..:|.....||.....|..|.||:|
 Worm   130 LVLMDARRSHKILNFYTSENP------TLRQMVTRSKGSRMVLKKATQEVNIHE----------- 177

  Fly   302 DVCESMKQQLLTL---VEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSN 363
                   ...||:   ||....:.....:..:|::.|||..:.:.|:|..:.|:      :|...
 Worm   178 -------WSFLTIYVSVEMFLNLDFMQNIDNEDKIVLLREFSLKTLVLNSAMRA------ILNKT 229

  Fly   364 NCVITRH----CPDPLVSP-NLD-ISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKG 422
            :.|:|..    .||.|:.. :|| ::.|.:|    |.|..:::.:...|...:..::|.:.....
 Worm   230 DRVMTPDGKDVYPDRLLQMFSLDFLNNIRSR----LATRFRELKVSSEEHMLLNLILFCNSALHP 290

  Fly   423 L-NEPHRIKSLRHQILNN--LEDYISDRQYESRGRFGEILLILPV----------LQSITWQMIE 474
            | :|..:..|.|.::.::  |:..:|..|.....||.::|.|..|          |.|:....:.
 Worm   291 LSDETKKTLSARQKVYSSALLQLCLSTYQQTGPSRFADLLSICHVVNKTVEDVTYLTSLFKLQMP 355

  Fly   475 QIQFAKIF-GVAHI 487
            .|::.|:| .|.|:
 Worm   356 FIEYKKLFVDVVHL 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	32/99 (32%)
		NR_LBD_HNF4_like	264..494	CDD:132729	52/247 (21%)
nhr-186	NP_504063.1	ZnF_C4	31..>80	CDD:197701	20/49 (41%)
		HOLI	179..339	CDD:214658	37/169 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910