Protein Alignment Hnf4 and nhr-185

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504061.2
• Gene: nhr-185 / 185907
• WormBaseID: WBGene00018539
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 371
• Identity: 96/371 - (25%)
• Similarity: 149/371 - (40%)
• Gaps: 78/371 - (21%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVD---KDKRNQCRYCRLRKCF 231
            |::|...|.|.:||..||:.||.||||.......|||....:|..:   ...|.:||.||.|||.
 Worm    31 CSVCCQLAFGLNYGVPSCNACKMFFRRMNIIKPSYTCLADGSCYTNFGFTHGRPKCRSCRFRKCL 95

  Fly   232 KAGMKKEAVQNERD-RISCRRTSNDDPDPGNGLSVI-SLVKAENESRQSKAGAAM---------E 285
            ..|||..:.:.|.: .:...::|.....|...::|. .|..:.|..||..|..||         :
 Worm    96 DVGMKYRSTEEEDEMMLIMLKSSTAQLQPDIFVTVADELYGSINSLRQLDARRAMNLETMRSDED 160

  Fly   286 PNINEDLSNKQFASINDVCESMKQQLL----------------TLVEWAKQIPAFNELQLDDQVA 334
            |.| |||..|.......:......||:                |.||:...:...:.|.::|::.
 Worm   161 PTI-EDLIKKSIRGFTTIQNPGSSQLVHQADQVLSQWTFFGIWTSVEFLNSLDFMSLLGIEDKLI 224

  Fly   335 LLRAHAGEHLLLGLSRRSMHLKDVLLLS--NNCVITRHCPDPLVSPN---LDISRI--------- 385
            :|::.|              |...||.|  ::|   ..|.|.||:|:   |..|||
 Worm   225 VLKSFA--------------LSSYLLSSAFHSC---SRCCDRLVNPDGTELYSSRIREMSEFSKD 272

  Fly   386 -GARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE--PHRIKSLRHQILNNLEDYIS-D 446
             ..||.:.|||.:..:.:...|:...:.::|..|...||::  ...|...:.:..|:|.:|.. .
 Worm   273 YADRIQEMLVTKICGLCLTPEEYILTQIILFCTPRLTGLSQFAQEIIGEQQKKYCNSLLEYCKLT 337

  Fly   447 RQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQ 492
            |......||.||:.|..||.    |..|.:|        |:.::|:
 Worm   338 RNTRGPARFQEIISIGSVLA----QCFEDVQ--------HLSTVLK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/77 (39%)
		NR_LBD_HNF4_like	264..494	CDD:132729	64/273 (23%)
nhr-185	NP_504061.2	ZnF_C4	31..100	CDD:197701	27/68 (40%)
		HOLI	197..356	CDD:214658	41/175 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910