Protein Alignment Hnf4 and nhr-142

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001263836.1
• Gene: nhr-142 / 185740
• WormBaseID: WBGene00018430
• Length: 441
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 106/417 - (25%)
• Similarity: 169/417 - (40%)
• Gaps: 108/417 - (25%)

  Fly   154 SQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFA-RNCVVDKD 217
            |:..:.|.....|.:.|.:|...|.|.|:|..||..|..||||||..:.:|:||.| :.|.:||.
 Worm    34 SRMSVDQPSSSSSDSECRVCAHTAHGVHFGVLSCRACAAFFRRSVVMDKKYSCRKASQGCRIDKS 98

  Fly   218 KRNQCRYCRLRKCFKAGMKKEAVQNERDRISC----RRTSNDDP---------DPGNGLSVISLV 269
            :|..||.||.:||.:.||..:.||..||.||.    |::..||.         .||:..|.:...
 Worm    99 ERYLCRLCRYKKCLQLGMTADNVQWNRDMISSTDRKRQSEEDDATDVDAYSDWSPGSKKSCLDAP 163

  Fly   270 KAENESRQSKAGAAMEPNINEDLSNKQFASIN-DVCESMKQQLLTL--VEWA-------KQIPAF 324
            ...:.||          .:|:  .:|.|.... .|.:.:.|...||  ::||       |::..|
 Worm   164 PLYDLSR----------TLNK--IHKTFMEFKIPVDDPVYQSTSTLGKMDWALRRHRKNKKMQNF 216

  Fly   325 ---NELQLDDQV----------ALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLV 376
               |.::||..|          |....|:.|...|.|..:....|.|..:|...        ..:
 Worm   217 RIINTIRLDQLVDMWGMEMTKQAEFMMHSEEFRELSLEEKFSIFKLVWQVSQRF--------EKL 273

  Fly   377 SPNLDISRIGARIIDELVTV--------MKDVGID---DTEFACIKALVFF--------DPNAKG 422
            :.:|:|  .|.|.|:|.:.:        |:||.||   .|::..::....|        :..|:.
 Worm   274 TMSLEI--FGKRAIEEKILITSNSTAIRMEDVEIDLSKITDYTSLELRKMFQHVCSQMYEEVARP 336

  Fly   423 LNE--PHRI---------------KSLRHQILNNLEDYISD----------RQYES---RGRFGE 457
            |.|  |..|               |:|:..||:..|.:|..          ::|:.   .||..:
 Worm   337 LMELDPSTIEISYMLCQIIWHIAGKTLQGDILDAGEKFIGKIADDLHQYYLKEYKMSNYAGRLIK 401

  Fly   458 ILLILPVLQSITWQMIEQIQFAKIFGV 484
            ::.::..||.|....::.::.||||.|
 Worm   402 LMTVVNSLQRIHLDRLKIMELAKIFEV 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	33/75 (44%)
		NR_LBD_HNF4_like	264..494	CDD:132729	61/293 (21%)
nhr-142	NP_001263836.1	ZnF_C4	50..119	CDD:197701	31/68 (46%)
		Hormone_recep	212..418	CDD:278530	43/215 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910