Protein Alignment Hnf4 and nhr-184

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001023926.1
• Gene: nhr-184 / 185730
• WormBaseID: WBGene00018415
• Length: 407
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 84/409 - (20%)
• Similarity: 161/409 - (39%)
• Gaps: 94/409 - (22%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVR--KNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFK 232
            |.||...|.|.|:|..||..|..||||:.|  :.....|.:. :|.:......:|:.|||:||:|
 Worm    11 CKICDLPAHGNHFGVLSCRACAAFFRRASRSPRFQDKACEYG-DCRIFDAGAYRCKICRLKKCYK 74

  Fly   233 AGMKKEAVQNERDRIS-----CRRTS------------------NDDPDPGNG----LSVISLV- 269
            .||.....|.:||.||     .:||.                  :.:|:..:.    :.|..||
 Worm    75 VGMDASKFQKDRDLISSSNAYLKRTKVYAPQSLANFLGRPEFIISFEPEKASPFKTVIDVTDLVH 139

  Fly   270 KAENESRQSKAGAAMEPNIN----------EDL----SNKQFASINDV--CESM---KQQLLTLV 315
            ||....::..|.:.|....:          |||    ||.:...:.::  .||:   :|..|...
 Worm   140 KAAEIFQEDLANSPMPYKYSNSLEKLTLEMEDLRLRSSNHKVKIVRNIGKAESLVFFEQMFLATA 204

  Fly   316 EWAKQIPAFNELQLDDQVALLRA---------------------HAGEHLLLGLSRRSMHLKDVL 359
            .|..::|.|..|.|..::.:|::                     ..|.::.:......::::|:.
 Worm   205 NWYARLPDFTSLDLRVKLEILKSTWMLWIRLNKLAETAQNQRIKEMGANIFMCSENTCLNVQDIN 269

  Fly   360 LLSNNCVITRHCPDPL---VSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAK 421
            :..:.|  |.:..:.:   :.||:|  :...:.:::||.      ::.|:......|:....|..
 Worm   270 VDWSWC--TNYGAEQMQAFLMPNID--KHWRQPVEDLVK------LNPTDMELNFMLIQLCLNDA 324

  Fly   422 GLNEPHRIKSLRHQIL----NNLEDYISDR----QYESRGRFGEILLILPVLQSITWQMIEQIQF 478
            |.....|:.....::|    :||.:|.:.:    .|.  ||..:::.|..:::....:..|:.:.
 Worm   325 GKKFQGRVLEATDKLLQINADNLHNYYTKKLNMPSYS--GRLTKLMKINQIVEEDVRERKEKAKI 387

  Fly   479 AKIFGVAHIDSLLQEMLLG 497
            .::|.:..|.....||..|
 Worm   388 VEVFDLFSIVYSHPEMFEG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/76 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	47/281 (17%)
nhr-184	NP_001023926.1	ZnF_C4	10..80	CDD:197701	26/69 (38%)
		Hormone_recep	177..384	CDD:278530	34/218 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910