Protein Alignment Hnf4 and nhr-177

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503455.1
• Gene: nhr-177 / 184557
• WormBaseID: WBGene00017503
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 338
• Identity: 68/338 - (20%)
• Similarity: 130/338 - (38%)
• Gaps: 71/338 - (21%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRR-SVRKNHQYTCRFAR-NCVVDKDKRNQCRYCRLRKCFK 232
            |.||.::..|.|:|..||..|..|||| ...|.::..||.:: .|..:|:.:..|:.|||.:||:
 Worm    34 CRICFEKGHGYHFGVFSCRACAAFFRRCHFLKENRRRCRLSKGKCGPNKNGKWFCKTCRLERCFR 98

  Fly   233 AGMKKEAVQNERD--RISCRR---TSNDDPDPGNGLSVISLVKAENE------------------ 274
            .||....:|.:||  :.|.::   ::.:..:|....:.:.|:...::
 Worm    99 LGMTPSNIQYDRDAYKSSVKKIKDSAENITEPKRDATSLILINKTSQVLPYVDLSQLVNKATRML 163

  Fly   275 -----SRQSKAGAAMEP----------NINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAF 324
                 ::::|..:.:|.          :..::|:.....|::||.:.|::.:....:|.......
 Worm   164 LNPIFTKKTKKMSNLEQLTHGLIELQWSQKDNLAEVVHLSVSDVTQDMERSMFGAAKWMMCSERI 228

  Fly   325 NELQLDDQVALLRA---HAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIG 386
            ...|...::.:|:|   ..|.     |.|.:...|  |.|...|........|:.:.|||.....
 Worm   229 RNYQDSLKIRILQAIWYTWGR-----LERIATTAK--LRLEKKCEEKHFVFSPMFALNLDEMSFD 286

  Fly   387 AR-------------------IIDELVTVMKDVGIDDTEFACIKALVFFDPNAK--GLNEPHRIK 430
            |.                   ..::.|..|.:|..:|.|...|...:.|....|  |.....::.
 Worm   287 ASCWTTLPFEEMQYFYVPRELFYEDAVLEMMEVKPNDVETTFIICSICFHLTGKRFGGEIQEKMD 351

  Fly   431 SLRHQILNNLEDY 443
            .|:..:.|:|.:|
 Worm   352 HLQDVLSNDLHEY 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/76 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	37/237 (16%)
nhr-177	NP_503455.1	ZnF_C4	34..104	CDD:197701	26/69 (38%)
		Hormone_recep	201..404	CDD:365875	33/171 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910