Protein Alignment Hnf4 and nhr-137

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001024506.1
• Gene: nhr-137 / 183865
• WormBaseID: WBGene00003727
• Length: 432
• Species: Caenorhabditis elegans
• Alignment Length: 402
• Identity: 97/402 - (24%)
• Similarity: 153/402 - (38%)
• Gaps: 114/402 - (28%)

  Fly   134 NNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQ-SPTVCAICGDRATGKHYGASSCDGCKGFFRRS 197
            :||..:||:..|.|.|.::|.:..:.|.:::: ....||:|...|||.||..:||:|||.||||.
 Worm    30 SNSWSTPNSTPSPSLSKSSSPKPTVSQAKERRVFDLPCAVCLYPATGYHYNVASCNGCKTFFRRC 94

  Fly   198 VRKNHQYTC-RFARNCVVD----KDKRNQCRYCRLRKCFKAGMKKEAVQ-----NERD------- 245
            |.....|.| |...||:::    ...|.:||.|||.:|.:.||:||||.     ||..
 Worm    95 VLSGSSYRCIRGDSNCLLNMRLVAGARIKCRSCRLDRCLQQGMRKEAVTSGIVGNEEKVAPQTAY 159

  Fly   246 --RISCRRTSNDDPDPGNGLSVISLVKAENESRQS--------KAGAAME------------PNI 288
              .||...||...|......|.:         ||:        |....:|            |:.
 Worm   160 LASISLPSTSTAIPKVTETASCL---------RQTLRLITKFRKCNIIVEKIDLHISALLTMPSF 215

  Fly   289 NEDLSNKQFAS--INDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHA----------- 340
            .::|:|.|..:  ..|:.|.....||..:|:||::|..::....|:..|:|...
 Worm   216 LDNLNNYQEETDFKRDLPEWCTIDLLCAIEFAKKLPDLSKFSDSDKEELIRNSCFTIAIAIEAIE 280

  Fly   341 -------------GEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDE 392
                         |..::..|:.....:..|......|::     |||...:.        .|||
 Worm   281 SYFDKKKTVVMPDGTDVMQSLANSGSVIHAVFTQMFVCIL-----DPLHRESF--------TIDE 332

  Fly   393 LVTVMKDVGIDDTEFACIKALVFF--------DPNAKGLNEPHRIKSLRHQILNNLEDYISDRQY 449
            ||..::              |:||        .|..|...| ..:||..|.::..|   |:....
 Worm   333 LVLTLQ--------------LLFFTIAAPENLTPEGKEQLE-KSVKSSMHCLMVLL---ITQNTT 379

  Fly   450 ESRGRFGEILLI 461
            ....|:|.::.:
 Worm   380 NFSARYGSLIAL 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	38/84 (45%)
		NR_LBD_HNF4_like	264..494	CDD:132729	45/252 (18%)
nhr-137	NP_001024506.1	NR_DBD_like	67..142	CDD:143512	34/74 (46%)
		HOLI	237..398	CDD:214658	34/186 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010